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Table 3 Differences in cognitive test among patients with or without pathologic values of Homocysteine, 25-OH D Vitamin and B12 Vitamin

From: The impact of homocysteine, B12, and D vitamins levels on functional neurocognitive performance in HIV-positive subjects

Cognitive test

Homocysteine

p-value a

25-OH D Vitamin

p-value a

B-12 Vitamin

 

Non-Pathologic (n = 17)

Pathologic (n = 40)

Non-Pathologic (n = 49)

Pathologic (n = 8)

Non-Pathologic (n = 49)

Pathologic (n = 8)

p-value a

Rey word BT

38.0 (31.0–43.3)

39.0 (32.5–44.3)

0.897

39.5 (34.0–44.3)

31.0 (22.5–38.8)

0.144

39.5 (33.5–45.5)

39.0 (23.0–40.5)

0.395

Rey word LT

7.0 (4.0–10.0)

8.0 (6.0–9.8)

0.401

7.0 (5.0–9.8)

5.5 (4.0–7.8)

0.195

7.5 (5.0–10.0)

7.0 (4.0–9.0)

0.421

Verbal Span Forward

5.0 (3.0–6.0)

5.0 (4.0–6.0)

0.615

5.0 (4.0–6.0)

5.0 (5.0–5.8)

0.589

5.0 (4.0–6.0)

5.0 (2.5–5.5)

0.873

Spatial Span Forward

4.0 (3.0–5.0)

3.5 (3.0–5.0)

0.662

4.0 (3.0–5.0)

4.0 (3.0–5.0)

0.874

4.0 (3.0–5.0)

5.0 (2.5–5.5)

0.567

Stroop E Test

2.0 (1.8–3.5)

1.0 (0–2.0)

0.040

1.0 (0–2.0)

3.0 (2.0–10.8)

0.049

1.5 (0–2.0)

4.0 (0.5–9.5)

0.155

Stroop T Test

20.0 (13.5–38.5)

17.0 (12.3–26.0)

0.565

17.0 (13.3–26.0)

24.0 (14.5–39.5)

0.065

16.0 (12.8–26.3)

26.0 (17.0–50.0)

0.185

Trail B T

154.0 (107.0–236.3)

137.5 (92.3–213.0)

0.660

131.5 (96.0–195.3)

281.0 (152.3–403.8)

0.035

133.5 (93.8–198.8)

338.0 (186.5–387.5)

0.002

Trail B E

1.0 (0–1.8)

0 (0–2.0)

0.298

0 (0–2.0)

1.5 (0.3–3.5)

0.408

0 (0–1.3)

2.0 (0–4.0)

0.257

Drawings

5.5 (4.0–6.0)

4.5 (2.3–6.0)

0.170

4.5 (3.0–6.0)

2.0 (0–5.5)

0.157

5.0 (4.0–6.0)

2.0 (0.5–4.0)

0.054

Verbal Fluency

24.0 (17.0–33.3)

36.5 (29.3–48.0)

0.003

34.5 (29.0–41.5)

23.0 (16.0–42.0)

0.629

34.5 (27–47.3)

24.0 (17.0–39.5)

0.237

Wais Digit Span

29.5 (19.3–49.3)

33.5 (21.5–44.0)

0.909

32.0 (23.0–44.0)

12.5 (6.8–29.5)

0.042

33.5 (22.5–46.3)

9.0 (6.5–32.0)

0.029

Double Barrage

12.0 (9.0–12.3)

11.0 (10.0–12.8)

0.836

11.5 (10.3–12.0)

10.5 (9.3–12.5)

0.195

11.0 (10.0–12.0)

13.0 (9.5–13.0)

0.395

Pegboard Dominant

76.0 (66.5–79.8)

73.5 (64.5–87.8)

0.945

75.0 (67.0–80.0)

97.5 (71.3–145.5)

0.376

72.0 (64.8–80.0)

100.0 (81.0–131.0)

0.014

Pegboard Non-Dominant

75.5 (69.0–86.8)

77.0 (68.3–90.5)

0.982

77.5 (69.3–85.8)

96.5 (78.5–146.8)

0.075

75.0 (67.5–87.5)

83.0 (76.5–131.5)

0.095

Zung Depression Score

43.5 (33.5–53.0)

34.5 (29.3–44.8)

0.060

36.5 (29.3–48.0)

45.5 (41.3–56.5)

0.755

38.0 (30.8–46.0)

44.0 (31.0–53.0)

0.506

  1. aMann-Whitney U test
  2. bolded p-value were significant after FDR correction
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BMC Infectious Diseases

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