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Table 3 Differences in cognitive test among patients with or without pathologic values of Homocysteine, 25-OH D Vitamin and B12 Vitamin

From: The impact of homocysteine, B12, and D vitamins levels on functional neurocognitive performance in HIV-positive subjects

Cognitive test Homocysteine p-value a 25-OH D Vitamin p-value a B-12 Vitamin  
Non-Pathologic (n = 17) Pathologic (n = 40) Non-Pathologic (n = 49) Pathologic (n = 8) Non-Pathologic (n = 49) Pathologic (n = 8) p-value a
Rey word BT 38.0 (31.0–43.3) 39.0 (32.5–44.3) 0.897 39.5 (34.0–44.3) 31.0 (22.5–38.8) 0.144 39.5 (33.5–45.5) 39.0 (23.0–40.5) 0.395
Rey word LT 7.0 (4.0–10.0) 8.0 (6.0–9.8) 0.401 7.0 (5.0–9.8) 5.5 (4.0–7.8) 0.195 7.5 (5.0–10.0) 7.0 (4.0–9.0) 0.421
Verbal Span Forward 5.0 (3.0–6.0) 5.0 (4.0–6.0) 0.615 5.0 (4.0–6.0) 5.0 (5.0–5.8) 0.589 5.0 (4.0–6.0) 5.0 (2.5–5.5) 0.873
Spatial Span Forward 4.0 (3.0–5.0) 3.5 (3.0–5.0) 0.662 4.0 (3.0–5.0) 4.0 (3.0–5.0) 0.874 4.0 (3.0–5.0) 5.0 (2.5–5.5) 0.567
Stroop E Test 2.0 (1.8–3.5) 1.0 (0–2.0) 0.040 1.0 (0–2.0) 3.0 (2.0–10.8) 0.049 1.5 (0–2.0) 4.0 (0.5–9.5) 0.155
Stroop T Test 20.0 (13.5–38.5) 17.0 (12.3–26.0) 0.565 17.0 (13.3–26.0) 24.0 (14.5–39.5) 0.065 16.0 (12.8–26.3) 26.0 (17.0–50.0) 0.185
Trail B T 154.0 (107.0–236.3) 137.5 (92.3–213.0) 0.660 131.5 (96.0–195.3) 281.0 (152.3–403.8) 0.035 133.5 (93.8–198.8) 338.0 (186.5–387.5) 0.002
Trail B E 1.0 (0–1.8) 0 (0–2.0) 0.298 0 (0–2.0) 1.5 (0.3–3.5) 0.408 0 (0–1.3) 2.0 (0–4.0) 0.257
Drawings 5.5 (4.0–6.0) 4.5 (2.3–6.0) 0.170 4.5 (3.0–6.0) 2.0 (0–5.5) 0.157 5.0 (4.0–6.0) 2.0 (0.5–4.0) 0.054
Verbal Fluency 24.0 (17.0–33.3) 36.5 (29.3–48.0) 0.003 34.5 (29.0–41.5) 23.0 (16.0–42.0) 0.629 34.5 (27–47.3) 24.0 (17.0–39.5) 0.237
Wais Digit Span 29.5 (19.3–49.3) 33.5 (21.5–44.0) 0.909 32.0 (23.0–44.0) 12.5 (6.8–29.5) 0.042 33.5 (22.5–46.3) 9.0 (6.5–32.0) 0.029
Double Barrage 12.0 (9.0–12.3) 11.0 (10.0–12.8) 0.836 11.5 (10.3–12.0) 10.5 (9.3–12.5) 0.195 11.0 (10.0–12.0) 13.0 (9.5–13.0) 0.395
Pegboard Dominant 76.0 (66.5–79.8) 73.5 (64.5–87.8) 0.945 75.0 (67.0–80.0) 97.5 (71.3–145.5) 0.376 72.0 (64.8–80.0) 100.0 (81.0–131.0) 0.014
Pegboard Non-Dominant 75.5 (69.0–86.8) 77.0 (68.3–90.5) 0.982 77.5 (69.3–85.8) 96.5 (78.5–146.8) 0.075 75.0 (67.5–87.5) 83.0 (76.5–131.5) 0.095
Zung Depression Score 43.5 (33.5–53.0) 34.5 (29.3–44.8) 0.060 36.5 (29.3–48.0) 45.5 (41.3–56.5) 0.755 38.0 (30.8–46.0) 44.0 (31.0–53.0) 0.506
  1. aMann-Whitney U test
  2. bolded p-value were significant after FDR correction