Skip to main content

Table 2 Distribution of first and second used antibiotics in the year 2014

From: Consecutive antibiotic use in the outpatient setting: an extensive, longitudinal descriptive analysis of antibiotic dispensing data in the Netherlands

Antibiotic agent Single prescriptions
n (% of total)
Prolongations
n (% of total)
First used in a switch (drug A)a
n (% of total)
Second used in a switch (drug B)a
n (% of total)
amoxicillin 1,044,483 (24%) 18,924 (20%) 27,376 (18%) 12,264 (8%)
nitrofurantoin 717,571 (16%) 7922 (8%) 41,311 (27%) 8264 (5%)
amoxicillin/clavulanic acid 622,430 (14%) 22,259 (23%) 17,370 (11%) 33,862 (22%)
doxycycline 587,598 (13%) 8735 (9%) 17,699 (12%) 11,333 (7%)
azithromycin and clarithromycin 412,609 (9%) 7561 (8%) 9438 (6%) 24,079 (16%)
flucloxacillin 263,599 (6%) 13,871 (15%) 9931 (7%) 3515 (2%)
ciprofloxacin 233,127 (5%) 6168 (6%) 8131 (5%) 19,968 (13%)
pheneticillin 134,071 (3%) 1890 (2%) 5530 (4%) 991 (1%)
trimethoprim 72,794 (2%) 987 (1%) 6084 (4%) 8729 (6%)
fosfomycin 87,252 (2%) 844 (1%) 3129 (2%) 13,203 (9%)
others 208,017 (5%)b 6038 (6%)c 6568 (4%)d 16,359 (11%)e
total 4,383,551 (100%) 95,199 (100%) 152,567 (100%) 152,567 (100%)
  1. a Switches: drug A ➔ drug B
  2. b The group others consist of antibiotics representing ≤1% of total single prescriptions
  3. c The group others largely consist of clindamycin, representing 2% of the total prolongations. All others represent ≤1% of total prolongations
  4. d The group others consist of antibiotics representing ≤1% of the first ones used in a switch
  5. e The group others largely consist of sulfamethoxazole/trimethoprim, clindamycin and norfloxacin, representing 3, 2 and 2% of the second ones used in a switch. All other antibiotics represent ≤1% of the second ones used in a switch