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Table 2 Distribution of first and second used antibiotics in the year 2014

From: Consecutive antibiotic use in the outpatient setting: an extensive, longitudinal descriptive analysis of antibiotic dispensing data in the Netherlands

Antibiotic agent

Single prescriptions

n (% of total)

Prolongations

n (% of total)

First used in a switch (drug A)a

n (% of total)

Second used in a switch (drug B)a

n (% of total)

amoxicillin

1,044,483 (24%)

18,924 (20%)

27,376 (18%)

12,264 (8%)

nitrofurantoin

717,571 (16%)

7922 (8%)

41,311 (27%)

8264 (5%)

amoxicillin/clavulanic acid

622,430 (14%)

22,259 (23%)

17,370 (11%)

33,862 (22%)

doxycycline

587,598 (13%)

8735 (9%)

17,699 (12%)

11,333 (7%)

azithromycin and clarithromycin

412,609 (9%)

7561 (8%)

9438 (6%)

24,079 (16%)

flucloxacillin

263,599 (6%)

13,871 (15%)

9931 (7%)

3515 (2%)

ciprofloxacin

233,127 (5%)

6168 (6%)

8131 (5%)

19,968 (13%)

pheneticillin

134,071 (3%)

1890 (2%)

5530 (4%)

991 (1%)

trimethoprim

72,794 (2%)

987 (1%)

6084 (4%)

8729 (6%)

fosfomycin

87,252 (2%)

844 (1%)

3129 (2%)

13,203 (9%)

others

208,017 (5%)b

6038 (6%)c

6568 (4%)d

16,359 (11%)e

total

4,383,551 (100%)

95,199 (100%)

152,567 (100%)

152,567 (100%)

  1. a Switches: drug A âž” drug B
  2. b The group others consist of antibiotics representing ≤1% of total single prescriptions
  3. c The group others largely consist of clindamycin, representing 2% of the total prolongations. All others represent ≤1% of total prolongations
  4. d The group others consist of antibiotics representing ≤1% of the first ones used in a switch
  5. e The group others largely consist of sulfamethoxazole/trimethoprim, clindamycin and norfloxacin, representing 3, 2 and 2% of the second ones used in a switch. All other antibiotics represent ≤1% of the second ones used in a switch