Epidemiological characteristics, clinical manifestations, and treatment outcome of 139 paediatric Ebola patients treated at a Sierra Leone Ebola treatment center

Table 3 Multivariate logistic regression output of paediatric EVD patients sociodemographic and clinical factors associated with treatment outcomes

Patient symptoms	Crude OR	95% CI	Adjusted OR	95% CI
Sex-Male	3.57	1.56–8.64	13.36	2.07–156.18
Age group in years (5 to < 10)	1.72	0.66–4.54	0.55	0.06–4.74
Age group in years (10 to < 15)	5.48	1.95–17.16	0.16	0.01–3.02
Education	3.36	1.76–6.82	0.15	0.01–1.04
Fever	0.83	0.31–2.50	1.66	0.25–14.17
Headache	0.70	0.14–5.09	0.05	0.001–1.90
Chest pain	0.70	0.14–5.09	0.10	0.01–1.04
Abdominal pain	1.88	0.82–4.66	11.01	1.30–161.81
Cough	0.72	0.32–1.61	0.68	0.12–3.68
Diarrhoea	4.86	1.59–21.28	0.99	0.14–7.19
Vomiting	6.26	2.63–16.26	35.65	3.43–833.73
Fatigue	6.17	2.03–26.94	3.18	0.42–33.99
Bleeding	10.21	2.64–50.09	2.78	0.31–26.74
Difficulty swallowing	7.08	2.72–19.09	0.26	0.02–2.94
Conjunctivitis	4.67	1.72–2.82	17.38	1.53–342.21
Difficulty breathing	16.67	4.66–79.19	23.28	1.92–713.01

Table 3 shows the output of a univariate and a multivariate analysis of paediatric EVD patients sociodemographic and clinical variables associated with EVD treatment outcomes. The crude OR is obtained by a logistic regression model with only that one variable as predictor. The adjusted OR is obtained from a multivariate logistic regression model, starting with all available sociodemographic and clinical predictors, after a stepwise backward elimination using the Akaike Information Criterion (AIC)

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