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Table 2 Clinical symptoms, treatment outcome and case fatality rates of paediatric EVD patients treated at the 34 Military Hospital in Sierra Leone during the 2014–2016 EVD outbreak

From: Epidemiological characteristics, clinical manifestations, and treatment outcome of 139 paediatric Ebola patients treated at a Sierra Leone Ebola treatment center

EVD patients clinical symptoms N (%) Survived N (%) Died N (%) Case fatality rate (%) p-value*
Total 139 (100) 108 (77.7) 31 (22.3) 22.3  
Fever 115 (82.7) 90 (82.3) 25 (80.7) 21.7 0.79
Headache 132 (95.0) 103 (95.4) 29 (93.6) 22.0 0.65
Anorexia 138 (99.3) 107 (99.1) 31 (100.0) 22.5 1.00
Muscle pain 136 (97.8) 107 (99.1) 29 (93.6) 21.3 0.13
Chest pain 119 (98.6) 96 (88.9) 23 (74.2) 19.3 0.08
Abdominal pain 83 (59.7) 61 (56.5) 22 (71.0) 26.5 0.21
Cough 67 (48.0) 54 (50.0) 13 (41.9) 19.4 0.54
Diarrhoea 99 (71.3) 71 (65.7) 28 (90.3) 28.3 < 0.05
Vomiting 57 (41.0) 34 (31.5) 23 (74.2) 40.4 < 0.05
Fatigue 93 (67.0) 65 (60.2) 28 (90.3) 30.1 < 0.05
Skin rash 2 (1.4) 0 (0.0) 2 (6.5) 100.0 0.05
Bleeding 10 (7.2) 3 (2.8) 7 (22.6) 70.0 < 0.05
Difficulty swallowing 23 (16.6) 10 (9.3) 13 (41.9) 56.5 < 0.05
Conjunctivitis 20 (14.4) 10 (9.3) 10 (32.3) 50.0 < 0.05
Difficulty breathing 13 (9.4) 3 (2.8) 10 (32.3) 76.9 < 0.05
Stage one EVD infection 34 (24.5) 34 (31.5) 0 (0.0) 0.0 < 0.05
Stage two infection 89 (64.0) 71 (65.7) 18 (58.1) 20.2  
Stage three EVD infection 16 (11.5) 3 (2.8) 13 (41.9) 81.3  
  1. *p-value was obtained by applying chi square test by comparing the case fatality rates and clinical characteristics of paediatric EVD patients