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Table 6 Median delay times stratified by smear results and adjusted Pos-to-Neg HRs over ten years

From: Trend in risk of delay in diagnosis of new pulmonary tuberculosis in Northwest China from 2008 to 2017

Year Smear positive Smear negative Adjusted Pos:Neg (HR, 95%CI) P
N (%) Median delay time (IQR) N (%) Median delay time (IQR)
2008 518 61 (33–122) 777 58 (31–88) 0.77 (0.69–0.86) * <0.001
2009 551 43 (17–93) 1022 32 (15–70) 0.83 (0.74–0.93) * 0.001
2010 628 36 (17–70) 820 33 (17–66) 0.92 (0.83–1.02) * 0.124
2011 599 29 (14–59) 882 29 (15–59) 0.98 (0.88–1.09) * 0.742
2012 340 31 (14–60) 954 30 (13–58) 0.97 (0.86–1.11) * 0.693
2013 236 30 (15–61) 1023 29 (14–56) 0.91 (0.78–1.06) * 0.228
2014 169 29 (15–60) 1081 32 (15–60) 1.07 (0.90–1.26) * 0.453
2015 107 21 (12–39) 839 32 (15–62) 1.44 (1.17–1.78) * 0.001
2016 104 25 (14–62) 891 30 (13–59) 0.89 (0.72–1.10) * 0.268
2017 294 53 (20–184) 857 31 (15–62) 0.45 (0.39–0.52) * <0.001
2008–2017 3546 36 (17–74) 9146 32 (15–62) 0.86 (0.78–0.95)† 0.002
  1. Note: “*” Adjusted for age, gender by using two-level mixed-effects survival model
  2. “†” Adjusted for age, gender and years. The estimate of variance in level 2 was 0.32 with the standard error of 0.45. An LR test comparing the model with the one-level survival model didn’t favor the random-intercept model with P > 0.05