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Table 4 Treatment outcomes of patients in the studied hospitals (n = 508)

From: A prospective study of socio-demographic, clinical characteristics and treatment outcomes of children with tuberculosis in Sindh, Pakistan

Characteristics

Cured

n = 15 (3%)

Completed

n = 468 (92.1%)

Failed

n = 4 (0.8%)

Lost to follow-up

n = 9 (1.8%)

Died

n = 6 (1.2%)

Transferred out n = 6 (1.2%)

Total cases 508

P value*

Gender

 Male

7 (2.9)

223 (92.9)

2 (0.8)

2 (0.8)

3 (1.3)

3 (1.3)

240 (47.2)

0.800

 Female

8 (3)

245 (91.4)

2 (0.7)

7 (2.6)

3 (1.1)

3 (1.1)

268 (52.8)

Age (years)

  ≤ 2

00

167 (96)

00

3 (1.7)

4 (2.3)

00

174 (34.2)

<  0.001

 3–5

00

118 (98.3)

1 (0.8)

1 (0.8)

00

00

120 (23.6)

 6–10

6 (4.3)

126 (90.6)

2 (1.4)

2 (1.4)

2 (1.4)

1 (0.7)

139 (27.4)

 11–14

9 (12)

57 (76)

1 (1.3)

3 (4)

00

5 (6.7)

75 (14.8)

Residence

 Rural

7 (3.4)

185 (89.8)

2 (1)

7 (3.4)

4 (1.9)

1 (0.5)

206 (40.6)

0.114

 Urban

8 (2.6)

283 (93.7)

2 (0.7)

2 (0.7)

2 (0.7)

5 (1.7)

302 (59.4)

Weight (percentiles)

 Normal

3 (5.9)

43 (84.3)

00

2 (3.9)

1 (2)

2 (3.9)

51 (10)

0.165

 Underweight**

12 (2.6)

425 (93)

4 (0.9)

7 (1.5)

5 (1.1)

4 (0.9)

457 (90)

Type of TB

 PTB+

15

5 (17.2)

00

2 (6.9)

1 (3.4)

6 (20.7)

29 (5.7)

<  0.001

 PTB-

(51.7)

48 (92.3)

3 (5.8)

1 (1.9)

00

00

52 (10.3)

 PTBNS

00

308 (98.1)

1 (0.3)

5 (1.6)

1 (0.3)

00

315 (62)

 EPTB

00

107 (95.5)

00

1 (0.9)

4 (3.6)

00

112 (22)

Registration Category at baseline

 New

13 (2.7)

452 (93.2)

3 (0.6)

9 (1.9)

4 (0.8)

4 (0.8)

485 (95.5)

<  0.001

 Retreated

2 (8.7)

16 (69.6)

1 (4.3)

00

2 (8.7)

2 (8.7)

23 (4.5)

ADRs

 Yes

1 (1.5)

52 (77.6)

3 (4.5)

6 (9)

2 (3)

3 (4.5)

67 (13.2)

<  0.001

 No

14 (3.2)

416 (94.3)

1 (0.2)

3 (0.7)

4 (0.9)

3 (0.7)

441 (86.8)

BCG scar

 Present

14 (3.2)

398 (91.3)

3 (0.7)

9 (2.1)

6 (1.4)

6 (1.4)

436 (85.8)

<  0.001

 Absent

1 (1.4)

70 (97.2)

1 (1.4)

00

00

00

72 (14.2)

Baseline X-ray

 Normal

2 (1.5)

123 (93.9)

2 (1.5)

3 (2.3)

00

1 (0.8)

131 (25.8)

0.352

 Abnormal

13 (4.1)

287 (90.3)

2 (0.6)

5 (1.6)

6 (1.9)

5 (1.6)

318 (62.6)

 Not done

00

58 (98.3)

00

1 (1.7)

00

00

59 (11.6)

HHC with TB

 Yes

4 (3)

117 (86.7)

3 (2.2)

4 (3)

3 (2.2)

4 (3)

135 (26.6)

0.031

 No

11 (2.9)

351 (94.1)

1 (0.3)

5 (1.3)

3 (0.8)

2 (0.5)

373 (73.4)

TST

 Positive (≥ 10 mm)

12 (4.5)

247 (92.2)

1 (0.4)

5 (1.9)

2 (0.7)

1 (0.4)

268 (52.8)

0.082

 Negative (< 10 mm)

3 (1.3)

221 (92.1)

3 (1.3)

4 (1.7)

4 (1.7)

5 (2.1)

240 (47.2)

Monthly income of family (PKRs)

  <  5000

6000–10,000

1 (8.3)

6 (3.9)

9 (75)

142 (92.8)

00

1 (0.7)

2 (16.7)

1 (0.7)

00

1 (0.7)

00

2 (1.3)

12 (2.4)

153 (30.1)

0.123

 11,000–20,000

6 (2.4)

233 (92.1)

2 (0.8)

4 (1.6)

4 (1.6)

4 (1.6)

253 (49.8)

  > 20,000

2 (2.2)

84 (93.3)

1 (1.1)

2 (2.2)

1 (1.1)

00

90 (17.7)

Education of caregiver

 No formal education

10 (4.2)

211 (89)

3 (1.3)

7 (3)

2 (0.8)

4 (1.7)

237 (46.6)

<  0.001

 Primary

2 (1.6)

119 (96.7)

00

2 (1.6)

00

00

123 (24.2)

 Secondary

2 (2.6)

74 (94.9)

1 (1.3)

00

1 (1.3)

00

78 (15.4)

 College

1 (2.8)

33 (91.7)

00

00

1 (2.8)

1 (2.8)

36 (7.1)

 Graduation

00

31 (91.2)

00

00

2 (5.9)

1 (2.9)

34 (6.7)

  1. PTB- smear negative pulmonary TB, PTB+: smear positive pulmonary TB, PTBNS: pulmonary TB with unknown sputum, EPTB: extra-pulmonary TB, PKRs: Pakistan rupees, * statistically significant value ≤0.05, **< 5 percentiles, HHC: household contacts