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Table 4 Treatment outcomes of patients in the studied hospitals (n = 508)

From: A prospective study of socio-demographic, clinical characteristics and treatment outcomes of children with tuberculosis in Sindh, Pakistan

Characteristics Cured
n = 15 (3%)
Completed
n = 468 (92.1%)
Failed
n = 4 (0.8%)
Lost to follow-up
n = 9 (1.8%)
Died
n = 6 (1.2%)
Transferred out n = 6 (1.2%) Total cases 508 P value*
Gender
 Male 7 (2.9) 223 (92.9) 2 (0.8) 2 (0.8) 3 (1.3) 3 (1.3) 240 (47.2) 0.800
 Female 8 (3) 245 (91.4) 2 (0.7) 7 (2.6) 3 (1.1) 3 (1.1) 268 (52.8)
Age (years)
  ≤ 2 00 167 (96) 00 3 (1.7) 4 (2.3) 00 174 (34.2) <  0.001
 3–5 00 118 (98.3) 1 (0.8) 1 (0.8) 00 00 120 (23.6)
 6–10 6 (4.3) 126 (90.6) 2 (1.4) 2 (1.4) 2 (1.4) 1 (0.7) 139 (27.4)
 11–14 9 (12) 57 (76) 1 (1.3) 3 (4) 00 5 (6.7) 75 (14.8)
Residence
 Rural 7 (3.4) 185 (89.8) 2 (1) 7 (3.4) 4 (1.9) 1 (0.5) 206 (40.6) 0.114
 Urban 8 (2.6) 283 (93.7) 2 (0.7) 2 (0.7) 2 (0.7) 5 (1.7) 302 (59.4)
Weight (percentiles)
 Normal 3 (5.9) 43 (84.3) 00 2 (3.9) 1 (2) 2 (3.9) 51 (10) 0.165
 Underweight** 12 (2.6) 425 (93) 4 (0.9) 7 (1.5) 5 (1.1) 4 (0.9) 457 (90)
Type of TB
 PTB+ 15 5 (17.2) 00 2 (6.9) 1 (3.4) 6 (20.7) 29 (5.7) <  0.001
 PTB- (51.7) 48 (92.3) 3 (5.8) 1 (1.9) 00 00 52 (10.3)
 PTBNS 00 308 (98.1) 1 (0.3) 5 (1.6) 1 (0.3) 00 315 (62)
 EPTB 00 107 (95.5) 00 1 (0.9) 4 (3.6) 00 112 (22)
Registration Category at baseline
 New 13 (2.7) 452 (93.2) 3 (0.6) 9 (1.9) 4 (0.8) 4 (0.8) 485 (95.5) <  0.001
 Retreated 2 (8.7) 16 (69.6) 1 (4.3) 00 2 (8.7) 2 (8.7) 23 (4.5)
ADRs
 Yes 1 (1.5) 52 (77.6) 3 (4.5) 6 (9) 2 (3) 3 (4.5) 67 (13.2) <  0.001
 No 14 (3.2) 416 (94.3) 1 (0.2) 3 (0.7) 4 (0.9) 3 (0.7) 441 (86.8)
BCG scar
 Present 14 (3.2) 398 (91.3) 3 (0.7) 9 (2.1) 6 (1.4) 6 (1.4) 436 (85.8) <  0.001
 Absent 1 (1.4) 70 (97.2) 1 (1.4) 00 00 00 72 (14.2)
Baseline X-ray
 Normal 2 (1.5) 123 (93.9) 2 (1.5) 3 (2.3) 00 1 (0.8) 131 (25.8) 0.352
 Abnormal 13 (4.1) 287 (90.3) 2 (0.6) 5 (1.6) 6 (1.9) 5 (1.6) 318 (62.6)
 Not done 00 58 (98.3) 00 1 (1.7) 00 00 59 (11.6)
HHC with TB
 Yes 4 (3) 117 (86.7) 3 (2.2) 4 (3) 3 (2.2) 4 (3) 135 (26.6) 0.031
 No 11 (2.9) 351 (94.1) 1 (0.3) 5 (1.3) 3 (0.8) 2 (0.5) 373 (73.4)
TST
 Positive (≥ 10 mm) 12 (4.5) 247 (92.2) 1 (0.4) 5 (1.9) 2 (0.7) 1 (0.4) 268 (52.8) 0.082
 Negative (< 10 mm) 3 (1.3) 221 (92.1) 3 (1.3) 4 (1.7) 4 (1.7) 5 (2.1) 240 (47.2)
Monthly income of family (PKRs)
  <  5000
6000–10,000
1 (8.3)
6 (3.9)
9 (75)
142 (92.8)
00
1 (0.7)
2 (16.7)
1 (0.7)
00
1 (0.7)
00
2 (1.3)
12 (2.4)
153 (30.1)
0.123
 11,000–20,000 6 (2.4) 233 (92.1) 2 (0.8) 4 (1.6) 4 (1.6) 4 (1.6) 253 (49.8)
  > 20,000 2 (2.2) 84 (93.3) 1 (1.1) 2 (2.2) 1 (1.1) 00 90 (17.7)
Education of caregiver
 No formal education 10 (4.2) 211 (89) 3 (1.3) 7 (3) 2 (0.8) 4 (1.7) 237 (46.6) <  0.001
 Primary 2 (1.6) 119 (96.7) 00 2 (1.6) 00 00 123 (24.2)
 Secondary 2 (2.6) 74 (94.9) 1 (1.3) 00 1 (1.3) 00 78 (15.4)
 College 1 (2.8) 33 (91.7) 00 00 1 (2.8) 1 (2.8) 36 (7.1)
 Graduation 00 31 (91.2) 00 00 2 (5.9) 1 (2.9) 34 (6.7)
  1. PTB- smear negative pulmonary TB, PTB+: smear positive pulmonary TB, PTBNS: pulmonary TB with unknown sputum, EPTB: extra-pulmonary TB, PKRs: Pakistan rupees, * statistically significant value ≤0.05, **< 5 percentiles, HHC: household contacts