Fig. 1From: TLR9 polymorphism correlates with immune activation, CD4 decline and plasma IP10 levels in HIV patientsTLR9 1635AA genotype is associated with lower CD4 counts in HIV infected patients: DNA was isolated from whole blood from 50 HIV infected patients and TLR9 1635 polymorphism determined by PCR-RFLP analysis. CD4 and CD8 levels from the patient blood samples were determined by immunostaining followed by flow cytometry. TLR9 1635AA or AG/GG genotypic groups were compared for (a) CD4 counts and (b) CD4:CD8 ratio. Patient population was subdivided into TLR9 1635AA, AG or GG genotypes and (c) CD4 counts and (d) CD4:CD8 ratio were compared. One tailed student’s t-test or Kruskal-Wallis test were used for statistical analysisBack to article page