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Table 5 Multivariate analysis of the incidence of aspergillosis

From: Effect of laminar air flow and building construction on aspergillosis in acute leukemia patients: a retrospective cohort study

variables Adjusted HR with model 1a p value Adjusted HR with model 2b p value
Neutropenia 0.45 0.362   
treatment periodc
 before construction (phase A) 1.97 0.463 1.76 0.540
 during construction (phase B) 3.42 0.184 3.60 0.170
 the late period after moving (phase D) 5.65 0.035 5.28 0.030
antifungal prophylaxisd 0.88 0.818 0.82 0.800
ALL vs AML 0.46 0.348 0.56 0.480
age 0.81 0.709 0.86 0.690
  1. AML denotes acute myelogenous leukemia; ALL, acute lymphoblastic leukemia; HR, hazard ratio
  2. aModel 1 is a Cox proportional hazards ratio model with time-dependent covariates
  3. bModel 2 is a Fine and Gray proportional hazard regression model
  4. cHR is calculated by comparison of the incidence in each period with in the early period after moving
  5. dHR is the ratio of the incidence in patients who received fluconazole with mold-active agent prophylaxis with the incidence in patients who received fluconazole-only prophylaxis