Skip to main content

Advertisement

Table 2 Reported leptospirosis complications

From: Estimating the burden of leptospirosis in Sri Lanka; a systematic review

Complication Published Year Citation Method of
Confirmation
Number
of patients
Total
patients
Percentage
Renal involvement 1964
1966
1970
1974
1976
2008
2008
2011
2011
2011
2012
2012
2013
2013
2013
2014
2014
2014
2015
2015
2015
2015
2015
2016
2016
2016
2016
2016
2016
2016
2017
[32]
[33]
[34]
[21]
[35]
[36]
[37]
[38]
[39]
[20]
[40]
[41]
[42]
[43]
[44]
[45]
[46]
[29]
[47]
[22]
[48]
[49]
[50]
[19]
[9]
[51]
[52]
[53]
[54]
[55]
[56]
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Autopsy
Biochemical
Biochemical
Biochemical
N/M
Biochemical
Biochemical
Biochemical
Autopsy
Biochemical
Proteinuria
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
Biochemical
44
13
C/S
41
34
11
C/R
23
C/S
62
10
a
N/M
C/R
12
N/M
a
7
C/R
C/R
157
14
N/M
25
10
N/M
C/S
60
213
113
a
60
104
C/S
81
61
45
C/R
155
C/S
132
62
a
N/M
C/R
22
N/M
a
32
C/R
C/R
232
19
N/M
45
48
66
C/S
110
563
221
a
73.3
12.5
C/S
50.6
55.9
24.4
C/R
14.8
C/S
46.9
16.1
a
N/M
C/R
54.5
30.0
a
21.8
C/R
C/R
67.7
73.3
7.14
55.6
20.8
68.2
C/S
54.5
37.8
51.1
a
Liver involvement 1964
1966
1967
1974
1976
2003
2011
2011
2011
2011
2012
2013
2013
2014
2014
2015
2015
2015
2015
2015
2016
2016
2016
2016
2016
2016
[32]
[33]
[57]
[21]
[35]
[58]
[38]
[39]
[20]
[59]
[41]
[42]
[44]
[45]
[29]
[60]
[48]
[47]
[22]
[49]
[19]
[53]
[9]
[51]
[54]
[55]
Biochemical
Biochemical
Clinical
Biochemical
Biochemical
Imaging
Biochemical
Biochemical
Biochemical
Clinical
Autopsy
Biochemical
Biochemical
N/M
Biochemical
Biochemical
Biochemical
Biochemical
Autopsy
Biochemical
Biochemical
Biochemical
Biochemical
Clinical
Biochemical
Biochemical
38
15
10
40
34
C/R
57
C/S
23
N/M
a
N/M
2
N/M
15
C/R
4
C/R
C/R
8
N/M
N/M
26
N/M
97
3
58
104
60
81
61
C/R
155
C/S
132
a
a
N/M
22
N/M
32
C/R
232
C/R
C/R
19
N/M
110
48
66
563
221
65.5
14.4
16.6
49.0
55.9
C/R
36.7
C/S
17.4
a
a
N/M
9.0
30.0
46.8
C/R
1.7
C/R
C/R
42.1
N/M
1.8
54.2
33.3
17.2
1.4
Cardiac involvement 1964
1977
2008
2008
2011
2011
2012
2012
2013
2013
2014
2014
2015
2015
2015
2015
2015
2015
2016
2016
2016
2016
2016
2016
[32]
[61]
[36]
[62]
[38]
[20]
[63]
[41]
[43]
[44]
[45]
[29]
[60]
[64]
[22]
[48]
[49]
[50]
[19]
[9]
[52]
[53]
[54]
[55]
ECG
Postmortem
ECG, Imaging
ECG, Imaging
Imaging
Imaging
ECG, Imaging
Autopsy
ECG, Imaging
ECG, Imaging
N/M
ECG, Imaging
ECG, Imaging
ECG, Imaging
Autopsy
ECG, Imaging
Clinical
ECG
ECG, Imaging
9
C/S
7
C/R
11
71
8
a
C/R
13
N/M
5
C/R
C/R
C/R
5
N/M
N/M
37
6
C/S
N/M
23
5
63
C/S
45
C/R
155
132
62
a
C/R
22
N/M
32
C/R
C/R
C/R
232
19
N/M
45
48
C/S
110
563
221
14.3
C/S
15.5
C/R
7.1
53.7
12.9
a
C/R
59.0
35.0
15.6
C/R
C/R
C/R
2.2
36.8
14.2
82.2
12.5
C/S
4.5
4.1
2.3
Lung involvement 1964
1977
2008
2008
2011
2011
2012
2013
2013
2015
2015
2015
2016
2016
2016
2016
2016
[32]
[61]
[36]
[62]
[39]
[20]
[41]
[43]
[44]
[60]
[22]
[48]
[19]
[52]
[55]
[53]
[54]
Clinical
Postmortem
Imaging
Imaging
Imaging
Imaging
Autopsy
Imaging
Imaging
Imaging
Autopsy
Imaging
Imaging
Imaging
Imaging
Imaging
Imaging
22
C/S
14
C/R
C/S
60
a
C/R
2
C/R
C/R
6
N/M
C/S
3
N/M
43
63
C/S
45
C/R
C/S
132
a
C/R
22
C/R
C/R
232
N/M
C/S
221
110
563
34.9
C/S
31.1
C/R
C/S
45.4
a
C/R
9.0
C/R
C/R
2.6
N/M
C/S
1.4
4.5
7.6
Neurological involvement 1964
1967
1974
2003
2008
2011
2011
2012
2014
2015
2016
[32]
[57]
[21]
[58]
[36]
[38]
[39]
[41]
[45]
[64]
[51]
Biochemical
Clinical
Clinical
Biochemical
Biochemical
Clinical
Clinical
Autopsy
N/M
Clinical
N/M
8
5
6
C/R
3
13
C/S
a
N/M
C/R
N/M
63
60
81
C/R
45
155
C/S
a
N/M
C/R
66
12.7
8.3
7.4
C/R
6.6
8.3
C/S
a
25.0
C/R
15.2
Pancreatic involvement 2008
2013
2016
2016
[37]
[43]
[52]
[54]
Biochemical
Biochemical
Biochemical
Biochemical
C/R
C/R
C/S
5
C/R
C/R
C/S
563
C/R
C/R
C/S
0.9
Bleeding manifestation 1959
1964
1966
1967
2011
2016
[12]
[32]
[33]
[57]
[39]
[53]
Clinical
Clinical
Clinical
Clinical
Clinical
Clinical
C/S
9
1
2
C/S
N/M
C/S
63
104
60
C/S
110
C/S
14.3
0.09
3.3
C/S
30.9
Splenic involvement 1964
2011
[32]
[59]
Clinical
Clinical
2
N/M
63
a
3.2
a
  1. C/S Case series, C/R Case report, N/M Not mentioned
  2. anot possible to calculate