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Table 2 The comparisons of biomarkers in peripheral blood and pleural effusion between TPE and MPE

From: Pleural IFN-γ release assay combined with biomarkers distinguished effectively tuberculosis from malignant pleural effusion

  TPE median (90%range) n MPE median (90% range) n P value AUC (95%CI)
Blood tests
 ESR (mm/h) 57 (26.30–97.70) 136 35 (5.30–72.90) 52 < 0.001 0.73 (0.65–0.81)
 CRP (mg/L) 79.54 (25.10–130.70) 126 17.15 (2.90–84.41) 30 < 0.001 0.75 (0.67–0.84)
Effusion tests
 WCC (106/L) 3989 (580.80–10,544) 91 1772 (504.60–3966) 58 < 0.001 0.74 (0.64–0.84)
 Monocytes (%) 76.25 (39.90–91.10) 139 76.55 (38.20–91.20) 58 0.30 0.55 (0.46–0.63)
 LDH (IU/L) 689.52 (336.30–1226.15) 128 496 (179.11–2007.32) 58 0.15 0.57 (0.47–0.67)
 TP (g/L) 53.56 (44.90–60.51) 91 49.44 (37.00–65.50) 58 0.02 0.61 (0.51–0.71)
 GLU (mmol/L) 4.25 (2.00–6.00) 91 4.86 (0.20–7.70) 58 0.09 0.58 (0.48–0.68)
  1. Abbreviations: ESR erythrocyte sedimentation rate, CRP C-Reactive protein, WCC white cell count, LDH lactate dehydrogenase, TP total protein, GLU glucose