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Table 2 The comparisons of biomarkers in peripheral blood and pleural effusion between TPE and MPE

From: Pleural IFN-γ release assay combined with biomarkers distinguished effectively tuberculosis from malignant pleural effusion

 

TPE median (90%range)

n

MPE median (90% range)

n

P value

AUC (95%CI)

Blood tests

 ESR (mm/h)

57 (26.30–97.70)

136

35 (5.30–72.90)

52

< 0.001

0.73 (0.65–0.81)

 CRP (mg/L)

79.54 (25.10–130.70)

126

17.15 (2.90–84.41)

30

< 0.001

0.75 (0.67–0.84)

Effusion tests

 WCC (106/L)

3989 (580.80–10,544)

91

1772 (504.60–3966)

58

< 0.001

0.74 (0.64–0.84)

 Monocytes (%)

76.25 (39.90–91.10)

139

76.55 (38.20–91.20)

58

0.30

0.55 (0.46–0.63)

 LDH (IU/L)

689.52 (336.30–1226.15)

128

496 (179.11–2007.32)

58

0.15

0.57 (0.47–0.67)

 TP (g/L)

53.56 (44.90–60.51)

91

49.44 (37.00–65.50)

58

0.02

0.61 (0.51–0.71)

 GLU (mmol/L)

4.25 (2.00–6.00)

91

4.86 (0.20–7.70)

58

0.09

0.58 (0.48–0.68)

  1. Abbreviations: ESR erythrocyte sedimentation rate, CRP C-Reactive protein, WCC white cell count, LDH lactate dehydrogenase, TP total protein, GLU glucose