Table 2 Distribution of systematic inflammatory response syndrome, infections and organ dysfunction in patients admitted at the Department of Medicine with infection without SIRS, sepsis, severe sepsis and septic shock in an 18-month period
Variables | Infection without SIRS | Sepsis of any severity | Sepsis | Severe sepsis | Septic shock |
|---|---|---|---|---|---|
Total | n = 471 | n = 583 | n = 296 | n = 266 | n = 21 |
Bacteremia, n (%) | |||||
 No | 459 (97.5) | 496 (85.1) | 265 (89.5) | 216 (81.2) | 15 (71.4) |
 Yes | 12 (2.5) | 87 (14.9) | 31 (10.5) | 50 (18.8) | 6 (28.6) |
No. of sources of infection per patient, n (%) | |||||
 1 | 318 (67.5) | 380 (65.2) | 184 (62.2) | 183 (68.8) | 13 (62.0) |
 2 | 21 (4.5) | 57 (9.8) | 19 (6.4) | 35 (13.2) | 3 (14.3) |
 3 | 1 (0.2) | 3 (0.5) | 0 | 3 (1.1) | 0 |
Sites of infection, n (%)* | |||||
 CNS | 1 (0.2) | 3 (0.5) | 1 (0.3) | 2 (0.8) | 0 |
 Upper respiratory tract | 7 (1.5) | 7 (1.2) | 3 (1.0) | 4 (1.5) | 0 |
 Lower respiratory tract | 162 (34.4) | 245 (42.0) | 107 (36.1) | 129 (48.5) | 9 (43.0) |
 Cardiovascular | 3 (0.6) | 1 (0.2) | 1 (0.3) | 0 | 0 |
 Abdominal | 15 (3.2) | 16 (2.7) | 5 (1.7) | 9 (3.4) | 2 (9.5) |
 Genitourinary tract | 89 (18.9) | 119 (20.4) | 60 (20.3) | 57 (21.4) | 2 (9.5) |
 Skin-soft tissue/bone-joint | 49 (10.4) | 50 (8.6) | 26 (8.8) | 23 (8.6) | 1 (4.8) |
 Catheter infection | 15 (3.2) | 31 (5.3) | 6 (2.0) | 22 (8.3) | 3 (14.3) |
 Other infection | 23 (4.9) | 29 (5.0) | 13 (4.4) | 14 (5.3) | 2 (9.5) |
 Uncertain group with bacteremia | 0 | 10 (1.7) | 5 (1.7) | 5 (1.9) | 0 |
 Uncertain group without bacteremia | 131 (27.8) | 133 (22.8) | 88 (29.7) | 40 (15.0) | 5 (23.8) |
SIRS, n (%) | |||||
 Pulse rate | 149 (31.6) | 406 (69.6) | 216 (73.0) | 177 (66.5) | 13 (61.9) |
 Temperature | 75 (15.9) | 296 (50.8) | 164 (55.4) | 126 (47.4) | 6 (28.6) |
 Respiratory rate | 12 (2.5) | 427 (73.2) | 211 (71.3) | 198 (74.4) | 18 (85.7) |
 Leukocyte count | 73 (15.5) | 368 (63.1) | 187 (63.2) | 170 (63.9) | 11 (52.4) |
SOFA positive criteria, n (%) | |||||
 0 | 183 (38.9) | 148 (25.4) | 131 (44.3) | 17 (6.4) | 0 |
 1 | 181 (38.4) | 183 (31.4) | 115 (38.9) | 68 (25.6) | 0 |
 2 | 53 (11.3) | 126 (21.6) | 40 (13.5) | 83 (31.2) | 3 (14.3) |
 3+ | 54 (11.5) | 126 (21.6) | 10 (3.4) | 98 (36.8) | 18 (85.7) |
SIRS positive criteria, n (%) | |||||
 2 | 0 | 342 (58.7) | 190 (64.2) | 143 (53.8) | 9 (42.9) |
 3 | 0 | 203 (34.8) | 101 (34.1) | 93 (35.0) | 9 (42.9) |
 4 | 0 | 38 (6.5) | 5 (1.7) | 30 (11.3) | 3 (14.3) |
QSOFA, n (%) | |||||
 0 | 325 (69.0) | 245 (42.0) | 213 (72.0) | 32 (12.0) | 0 |
 1 | 126 (26.8) | 235 (40.3) | 79 (26.7) | 149 (56.0) | 7 (33.3) |
 2 | 19 (4.0) | 74 (12.7) | 4 (1.4) | 64 (24.1) | 6 (28.6) |
 3 | 1 (0.2) | 29 (5.0) | 0 | 21 (7.9) | 8 (38.1) |