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Table 3 Comparison of the groups with high and low IFN-γ and IL-6 levels among the patients on ART at diagnosis of HIV infection

From: Clinical characteristics of HIV-1-infected patients with high levels of plasma interferon-γ: a multicenter observational study

 

High IFN-γ

Low IFN-γ

P-value

High IL-6

Low IL-6

P-value

Clinical categories

  

0.7550

  

0.4122

 Acute HIV infection

7 (18%)

26 (17%)

 

4 (11%)

29 (19%)

 

 Chronic HIV infection, Category A/B

21 (54%)

89 (60%)

 

25 (66%)

85 (57%)

 

 Category C

11 (28%)

34 (23%)

 

9 (24%)

36 (24%)

 

CD4+ cell count (cell/μL), median [IQR]

265 [71–393]

253 [116–393]

0.9986

261 [107–386]

253 [104–398]

0.6920

HIV-1-RNA level (copies/mL), median [IQR]

96,750 [25,050–789,500]

105,000 [26,725–462,250]

0.9956

79,150 [25,475–373,250]

101,500 [26,100–491,500]

0.5009

Comorbidities

 Chronic renal disease (n, %)

0 (0%)

3 (2%)

1.0000

1 (2%)

2 (1%)

0.5089

 Chronic hepatitis B (n, %)

2 (5%)

12 (8%)

0.7391

2 (5%)

12 (8%)

0.7384

 Dyslipidemia (n, %)

2 (5%)

15 (9%)

0.5327

3 (7%)

14 (9%)

1.0000

 Hypertension (n, %)

0 (0%)

4 (3%)

0.5833

2 (5%)

2 (1%)

0.1949

 Diabetes mellitus (n, %)

0 (0%)

5 (3%)

0.5855

3 (7%)

2 (1%)

0.0635

  1. Abbreviations: IQR = interquartile range, HIV-1 = human immunodeficiency virus 1