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Table 3 Prognostic score performance in patients with complete data for multivariate model (N = 1113)

From: Development and validation of a risk score to predict mortality during TB treatment in patients with TB-diabetes comorbidity

Risk group

n (%)

Score, mean (±SD)

Mortality % (n)

P Value*

Low-risk group (< 12 points)

776 (63.7%)

4.8 (±3.8)

3.1% (24)

< 0.001

Medium-risk group (12–21 points)

233 (19.2%)

17.3 (±2.3)

12.9% (30)

High-risk group (≥22 points)

208 (17.1%)

27.7 (±7.3)

27.9% (58)

All patients with complete data (N = 1217)

1217 (100%)

11.1 (±10.0)

9.2% (112)

 

Discrimination assessment

 AUC (95% CI), final model in development

0.83 (0.79, 0.87)

 AUC (95% CI), final model in bootstrap validation

0.82 (0.78, 0.87)

Calibration assessment

 Hosmer-Lemeshow test

Chi-square = 4.54, p = 0.81

 Brier score

0.07

  1. Abbreviation: SD standard deviation, AUC Receiver Operating Characteristic (ROC) curve
  2. Score range: [0–68]; Comparisons of mortality between risk groups were conducted using Chi-square test; *Overall p-value. A p < 0.01 was also found for all pairwise comparisons among groups (i.e. low-risk vs. medium-risk, low-risk vs. high-risk and medium-risk vs. high-risk groups)
  3. Brier score: ranged from 0 to 1, the lower the Brier score is, the better the model is calibrated; Hosmer-Lemeshow test: non-significant p-value indicates the model is well calibrated