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Table 3 Prognostic score performance in patients with complete data for multivariate model (N = 1113)

From: Development and validation of a risk score to predict mortality during TB treatment in patients with TB-diabetes comorbidity

Risk group n (%) Score, mean (±SD) Mortality % (n) P Value*
Low-risk group (< 12 points) 776 (63.7%) 4.8 (±3.8) 3.1% (24) < 0.001
Medium-risk group (12–21 points) 233 (19.2%) 17.3 (±2.3) 12.9% (30)
High-risk group (≥22 points) 208 (17.1%) 27.7 (±7.3) 27.9% (58)
All patients with complete data (N = 1217) 1217 (100%) 11.1 (±10.0) 9.2% (112)  
Discrimination assessment
 AUC (95% CI), final model in development 0.83 (0.79, 0.87)
 AUC (95% CI), final model in bootstrap validation 0.82 (0.78, 0.87)
Calibration assessment
 Hosmer-Lemeshow test Chi-square = 4.54, p = 0.81
 Brier score 0.07
  1. Abbreviation: SD standard deviation, AUC Receiver Operating Characteristic (ROC) curve
  2. Score range: [0–68]; Comparisons of mortality between risk groups were conducted using Chi-square test; *Overall p-value. A p < 0.01 was also found for all pairwise comparisons among groups (i.e. low-risk vs. medium-risk, low-risk vs. high-risk and medium-risk vs. high-risk groups)
  3. Brier score: ranged from 0 to 1, the lower the Brier score is, the better the model is calibrated; Hosmer-Lemeshow test: non-significant p-value indicates the model is well calibrated