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Table 2 Microbial aetiology of CAP stratified by cardiac event

From: Cardiac events after macrolides or fluoroquinolones in patients hospitalized for community-acquired pneumonia: post-hoc analysis of a cluster-randomized trial

 

No cardiac event

Any cardiac event

 

Proven

Possible

Proven

Possible

Streptococcus pneumoniae

191 (12.8%)

48 (3.2%)

20 (17.4%)

1 (0.9%)

Haemophilus influenzae

5 (0.3%)

102 (6.9%)

1 (0.9%)

9 (7.8%)

Moraxella catarrhalis

16 (1.1%)

2 (1.7%)

Staphylococcus aureus

7 (0.5%)

41 (2.8%)

4 (3.5%)

Other gram positives

8 (0.5%)

11 (0.7%)

1 (0.9%)

Escherichia coli

7 (0.5%)

33 (2.2%)

2 (1.7%)

2 (1.7%)

Klebsiella pneumoniae

1 (0.1%)

10 (0.7%)

2 (1.7%)

Pseudomonas aeruginosa

29 (1.9%)

2 (1.7%)

Other gram negatives

5 (0.3%)

56 (3.8%)

6 (5.2%)

Legionella pneumophila

14 (0.9%)

1 (0.1%)

Mycoplasma pneumoniae

21 (1.4%)

Mycobacteria

2 (0.1%)

Viruses

40 (2.7%)

1 (0.9%)

Fungi / yeast

30 (2.0%)

1 (0.9%)

1 (0.9%)

No Pathogen

944 (63.4%)

74 (64.3%)

  1. Proven pathogens: based on pathogens detected in blood cultures, pleural fluid cultures, and urinary antigen tests (BINAX Now for S. pneumoniae and L. pneumophila). Possible pathogens: based on pathogens detected in sputum cultures, broncho-alveolar lavage fluid cultures, and serology. Candida species cultured from sputum and common skin contaminants from blood cultures where antibiotic treatment was not changed, were considered as contamination