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Table 2 Microbial aetiology of CAP stratified by cardiac event

From: Cardiac events after macrolides or fluoroquinolones in patients hospitalized for community-acquired pneumonia: post-hoc analysis of a cluster-randomized trial

  No cardiac event Any cardiac event
  Proven Possible Proven Possible
Streptococcus pneumoniae 191 (12.8%) 48 (3.2%) 20 (17.4%) 1 (0.9%)
Haemophilus influenzae 5 (0.3%) 102 (6.9%) 1 (0.9%) 9 (7.8%)
Moraxella catarrhalis 16 (1.1%) 2 (1.7%)
Staphylococcus aureus 7 (0.5%) 41 (2.8%) 4 (3.5%)
Other gram positives 8 (0.5%) 11 (0.7%) 1 (0.9%)
Escherichia coli 7 (0.5%) 33 (2.2%) 2 (1.7%) 2 (1.7%)
Klebsiella pneumoniae 1 (0.1%) 10 (0.7%) 2 (1.7%)
Pseudomonas aeruginosa 29 (1.9%) 2 (1.7%)
Other gram negatives 5 (0.3%) 56 (3.8%) 6 (5.2%)
Legionella pneumophila 14 (0.9%) 1 (0.1%)
Mycoplasma pneumoniae 21 (1.4%)
Mycobacteria 2 (0.1%)
Viruses 40 (2.7%) 1 (0.9%)
Fungi / yeast 30 (2.0%) 1 (0.9%) 1 (0.9%)
No Pathogen 944 (63.4%) 74 (64.3%)
  1. Proven pathogens: based on pathogens detected in blood cultures, pleural fluid cultures, and urinary antigen tests (BINAX Now for S. pneumoniae and L. pneumophila). Possible pathogens: based on pathogens detected in sputum cultures, broncho-alveolar lavage fluid cultures, and serology. Candida species cultured from sputum and common skin contaminants from blood cultures where antibiotic treatment was not changed, were considered as contamination