Fig. 1

Inclusion of patients and cardiac event rates per population. n/w new or worsening; BL beta-lactam; BLM beta-lactam combination with macrolide; FQL fluoroquinolone. The population for the primary analysis consisted of patients with a working diagnosis of CAP; the population for the sensitivity analysis consisted of the patients that developed radiological evidence of CAP during the first 48 h of admission. Crude new or worsening cardiac event rates are presented from the original trial arms for patients only receiving the cluster-randomized antibiotic strategy (per protocol) or who were non-adherent to the strategy