Skip to main content
Fig. 3 | BMC Infectious Diseases

Fig. 3

From: Transcription factors STAT-4, STAT-6 and CREB regulate Th1/Th2 response in leprosy patients: effect of M. leprae antigens

Fig. 3

Phosphorylated STAT-4 and STAT-6 expressing CD4+T cells in healthy individuals and leprosy patients. I Representative histogram showing CD4 + T cells expressing STAT-4 and STAT-6 in healthy individuals and leprosy patients. II Mean Percentage of pSTAT-4 and III pSTAT-6 expressing CD4+T cells in healthy individuals (H) and leprosy patients with or without stimulation with M. leprae antigens. PBMCs of different study subjects were incubated with medium only (A) or stimulated with MLSA, WCL and PGL-1antigens (B) and incubated for 24 h. After incubation cells were washed and stained with fluorescent labeled anti-CD3, anti-CD4, anti pSTAT-4 and anti pSTAT-6 antibodies and acquired in flow cytometer. * = p < 0.05. BT/TT (Borderline tuberculoid/Tuberculoid), BL/LL (Borderline lepromatous/Lepromatous)

Back to article page