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Table 3 Estimates of the amount of disease attributable to recent transmission calculated using the “n-1” method and retrospective clustering with cases up to two years beforehand, using all cases notified within different time periods during 2007–11

From: Mycobacterium tuberculosis transmission in an ethnically-diverse high incidence region in England, 2007–11

Time period

Number of cases clustered, excluding the first case

Number of cases notified during the study period

Number retrospectively clustered with cases up to 2 years previously

Number of cases with onset more than two years after the start of the study period

% due to recent transmission based on:

“n-1” formula

Retrospective clustering

2007–11

734

2159

452

1329

34% (32,36)

34% (31,37)

2007–10

554

1721

302

891

32% (30,34)

34% (31,37)

2007–9

393

1291

156

461

30% (28,33)

34% (30,38)

  1. Numbers in parentheses denote (exact binomial) 95% confidence intervals
  2. Only the cases who had onset two or more years after the start of the study period were used in the denominator for the retrospective clustering percentage