Fig. 5
From: Motility of human renal cells is disturbed by infection with pathogenic hantaviruses
Migration of podocytes inoculated with sera of patients with PUUV infection. Podocytes were inoculated with normal podocyte medium containing 10% FCS (−, white bars), medium containing 50% serum of healthy control individuals (ctrl, light grey bars), or with medium containing 50% serum of patients with PUUV infection collected during the clinical course (dark grey bars) and analyzed by migration assay. Sera were added 30 min before insert removal. Averaged migration of podocytes in the presence of sera derived from three healthy donors was set to 100%. Shown is mean ± SD. Levels of patients’ serum creatinine were shown on the right y-axis to monitor the clinical course of infection. Dashed horizontal line indicates the reference value of serum creatinine for healthy individuals. Dpo: days post onset