The incidence, risk factors and outcomes of early bloodstream infection in patients with malignant hematologic disease after unrelated cord blood transplantation: a retrospective study

Table 5 Univariate and multivariate analyses of risk factors for the early BSI after UCBT

Factor	BSI (n = 92)	non-BSI (n = 244)	Univariate analysis	Multivariate analysis
Factor	BSI (n = 92)	non-BSI (n = 244)	P	OR (95% CI)	P
Gender			0.634
Male	57	158
Female	35	86
Age [years]			0.037		0.164
<=14	53	170
> 14	39	74
Disease			< 0.001		0.007
AML	33	77
ALL	34	143		0.611(0.343–1.089)
CML	8	8		1.578(0.482–5.168)
MDS	12	10		2.752(1.015–7.464)
Others	5	6		2.870(0.769–10.710)
Conditioning regimen			0.001	1.755(1.008–3.057)	0.047
Not including TBI	49	178
Including TBI	43	66
State of disease			0.016		0.640
CR or Chronic phase	62	195
NR or Advanced phase	30	49
HLA match (low-resolution)			0.75
4/6	33	80
5/6	46	122
6/6	13	42
Total nucleated-cell dose			0.035		0.940
< =4.17 × 10⁷/kg	55	114
> 4.17 × 10⁷/kg	37	129
Total CD34⁺ cell dose			0.079		0.977
< =2.32 × 10⁵/kg	54	117
> 2.32 × 10⁵/kg	38	127
Time of neutrophil recovery			< 0.001	1.117(1.056–1.118)	0.000
< =17d	34	150
> 17d	58	94

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