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Table 5 Univariate and multivariate analyses of risk factors for the early BSI after UCBT

From: The incidence, risk factors and outcomes of early bloodstream infection in patients with malignant hematologic disease after unrelated cord blood transplantation: a retrospective study

Factor BSI (n = 92) non-BSI (n = 244) Univariate analysis Multivariate analysis
P OR (95% CI) P
Gender    0.634   
 Male 57 158    
 Female 35 86    
Age [years]    0.037   0.164
<=14 53 170    
  > 14 39 74    
Disease    < 0.001   0.007
 AML 33 77    
 ALL 34 143   0.611(0.343–1.089)  
 CML 8 8   1.578(0.482–5.168)  
 MDS 12 10   2.752(1.015–7.464)  
 Others 5 6   2.870(0.769–10.710)  
Conditioning regimen    0.001 1.755(1.008–3.057) 0.047
 Not including TBI 49 178    
 Including TBI 43 66    
State of disease    0.016   0.640
CR or Chronic phase 62 195    
NR or Advanced phase 30 49    
HLA match (low-resolution)    0.75   
 4/6 33 80    
 5/6 46 122    
 6/6 13 42    
Total nucleated-cell dose    0.035   0.940
  < =4.17 × 107/kg 55 114    
  > 4.17 × 107/kg 37 129    
Total CD34+ cell dose    0.079   0.977
  < =2.32 × 105/kg 54 117    
  > 2.32 × 105/kg 38 127    
Time of neutrophil recovery    < 0.001 1.117(1.056–1.118) 0.000
  < =17d 34 150    
  > 17d 58 94    
  1. OR odds ratio, CI confidence interval