Table 6 Test performance characteristics; comparison with earlier studies performed by other groups
From: Laboratory evaluation of four HIV/syphilis rapid diagnostic tests
| Â | SD Bioline HIV/Syphilis Duo | DPP HIV-Syphilis Assay | Multiplo Rapid TP/HIV Antibody Test | Insti Multiplex HIV-1/HIV-2/Syphilis Antibody Test |
|---|---|---|---|---|
Antibodies to HIV | ||||
 Sensitivity (%) | ||||
  This evaluation (95% CI) | 100 (98.2–100) | 100 (98.2–100) | 99.5 (97.2–100) | 99.5 (97.2–100) |
  Previous laboratory evaluationsa | 97.1–100 | 98.8–100 | 97.9–100 | 100 |
  Previous field evaluationsa | 98.8–99.2 | NA | 93.8 | 93.8 |
 Specificity (%) | ||||
  This evaluation | 99.5 (97.2–100) | 97.5 (94.3–99.2) | 99.5 (97.2–100) | 93.5 (89.1–96.5) |
  Previous laboratory evaluationsa | 99.5–100 | 97.9–98.7 | 91.9–98.3 | 95.5 |
  Previous field evaluationsa | 97.0–100 | NA | 100 | 100 |
Antibodies to Treponema pallidum | ||||
 Sensitivity (%) | ||||
  This evaluation (95% CI) | 87.0 (81.5–91.3) | 86.5 (81.0–90.9) | 73.5 (66.8–79.5) | 81.0 (74.9–86.2) |
  Previous laboratory evaluationsa | 72.2–100 | 82.5–98.8 | 80.7–94.6 | 87.4 |
  Previous field evaluationsa | 66.7–96.5 | NA | 81 | 81.0 |
 Specificity (%) | ||||
  This evaluation | 99.5 (97.2–100) | 100 (98.2–100) | 99.5 (97.2–100) | 99.0 (96.4–99.9) |
  Previous laboratory evaluationsa | 96.0–100 | 96.4–100 | 88.7–97.2 | 97.0 |
 Previous field evaluationsa | 90.8–98.8 | NA | 100 | 100 |