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Table 2 Performance characteristics

From: Laboratory evaluation of four HIV/syphilis rapid diagnostic tests

RDT HIV antibodies Treponema pallidum antibodies Final invalid rate (%)
Sensitivity (%) (95% CI) Specificity (%) (95% CI) Inter-reader variability (%) Sensitivity (%) (95% CI) Specificity (%) (95% CI) Inter-reader variability (%)
Initial Final Initial Final Initial Final Initial Final
SD Bioline HIV/Syphilis Duo 100 (98.2–100) 100 (98.2–100) 99.5 (97.2–100) 99.5 (97.2–100) 0 86.5 (81.0–90.9) 87.0 (81.5–91.3) 99.5 (97.2–100) 99.5 (97.2–100) 4.0 0
DPP HIV-Syphilis Assay 100 (98.2–100) 100 (98.2–100) 96.0 (92.3–98.3) 97.5 (94.3–99.2) 1.0 85.0 (79.3–89.6) 86.5 (81.0–90.9) 100 (98.2–100) 100 (98.2–100) 4.5 0
Multiplo Rapid TP/HIV Antibody Test 99.5 (97.2–100) 99.5 (97.2–100) 99.5 (97.2–100) 99.5 (97.2–100) 0.3 70.0 (63.1–76.3) 73.5 (66.8–79.5) 99.0 (96.4–99.9) 99.5 (97.2–100) 4.8 0.5
Insti Multiplex HIV-1/HIV-2/Syphilis Antibody Test 99.5 (97.2–100) 99.5 (97.2–100) 88.0 (82.7–92.2) 93.5 (89.1–96.5) 4.5 78.5 (72.2–84.0) 81.0 (74.9–86.2) 99.0 (96.4–99.9) 99.0 (96.4–99.9) 1.8 0