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Table 2 Proportion and 95% confidence interval for categorized measures of lowest CD4+ T-cell count and highest HIV viral load before cART for HIV-BCS and SISCEL databases

From: Validation of CD4+ T-cell and viral load data from the HIV-Brazil Cohort Study using secondary system data

  HIV-BCS SISCEL
N % (95%CI) N % (95%CI)
Full data
 CD4+ T-cell count (cell/mm3)
  < 200 3878 48.4 (47.3–49.6) 2857 35.7 (34.7–36.7)
  200 |-- 350 2722 34.0 (32.9–35.0) 2194 27.4 (26.4–28.4)
  > 350 812 10.1 (9.5–10.8) 803 10.0 (9.3–10.8)
  NDA 595 7.4 (6.9–8.0) 2153 26.9 (25.9–27.8)
  Total 8007 8007
 HIV viral loada
  Below 188 2.3 (2.0–2.7) 115 1.4 (1.2–1.7)
  Above 6844 85.5 (84.8–86.3) 5093 63.6 (62.6–64.6)
  NDA 975 12.2 (11.5–12.9) 2799 35.0 (33.9–36.0)
  Total 8007 8007
Disconsidering NDA
 CD4+ T-cell count (cell/mm3)
  < 200 2923 50.8 (49.5–52.1) 2811 48,9 (47.6–50.1)
  200 |-- 350 2131 37.0 (35.8–38.2) 2166 37.6 (36.4–38.9)
  > 350 699 12.2 (11.3–13.0) 776 13.5 (12.6–14.4)
  Total 5753 5753
 HIV viral loada
  Below 114 2.2 (1.8–2.6) 115 2.2 (1.8–2.6)
  Above 5094 97.8 (97.4–98.2) 5093 97.8 (97.4–98.2)
  Total 5208 5208
  1. 95% CI was based on 1000 bootstrap samples
  2. NDA No data available
  3. aViral load was grouped in: above or below assay lower limit of detection. The lower limit of detection varied according to method over the years between 400 and 40 copies / ml