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Table 2 Proportion and 95% confidence interval for categorized measures of lowest CD4+ T-cell count and highest HIV viral load before cART for HIV-BCS and SISCEL databases

From: Validation of CD4+ T-cell and viral load data from the HIV-Brazil Cohort Study using secondary system data

 

HIV-BCS

SISCEL

N

% (95%CI)

N

% (95%CI)

Full data

 CD4+ T-cell count (cell/mm3)

  < 200

3878

48.4 (47.3–49.6)

2857

35.7 (34.7–36.7)

  200 |-- 350

2722

34.0 (32.9–35.0)

2194

27.4 (26.4–28.4)

  > 350

812

10.1 (9.5–10.8)

803

10.0 (9.3–10.8)

  NDA

595

7.4 (6.9–8.0)

2153

26.9 (25.9–27.8)

  Total

8007

8007

 HIV viral loada

  Below

188

2.3 (2.0–2.7)

115

1.4 (1.2–1.7)

  Above

6844

85.5 (84.8–86.3)

5093

63.6 (62.6–64.6)

  NDA

975

12.2 (11.5–12.9)

2799

35.0 (33.9–36.0)

  Total

8007

8007

Disconsidering NDA

 CD4+ T-cell count (cell/mm3)

  < 200

2923

50.8 (49.5–52.1)

2811

48,9 (47.6–50.1)

  200 |-- 350

2131

37.0 (35.8–38.2)

2166

37.6 (36.4–38.9)

  > 350

699

12.2 (11.3–13.0)

776

13.5 (12.6–14.4)

  Total

5753

5753

 HIV viral loada

  Below

114

2.2 (1.8–2.6)

115

2.2 (1.8–2.6)

  Above

5094

97.8 (97.4–98.2)

5093

97.8 (97.4–98.2)

  Total

5208

5208

  1. 95% CI was based on 1000 bootstrap samples
  2. NDA No data available
  3. aViral load was grouped in: above or below assay lower limit of detection. The lower limit of detection varied according to method over the years between 400 and 40 copies / ml