Table 3 OPK activities of mAbs (EC50, ng/ml)
| Â | MOPA assay killing Pneumococcal serotypes | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotype | mAb | T4 | T6b | T14 | T23f | T18c | T19f | T9v | T6a | T1 | T3 | T5 | T6c | T7F | T19A | T22F | T33F |
T4 | 1A6 | 29 | – | – | – | – | – | – | – | ND | ND | ND | ND | ND | ND | ND | ND |
T4 | 1A10 | 55 | – | – | – | – | – | – | – | ND | ND | ND | ND | ND | ND | ND | ND |
T4 | 1B1 | 23 | – | – | – | – | – | – | – | ND | ND | ND | ND | ND | ND | ND | ND |
T18C | 1B2 | – | – |  | – | 47 | – | – | – | ND | ND | ND | ND | ND | ND | ND | ND |
T1 | 1C6 | ND | ND | ND | ND | ND | ND | ND | ND | 14 | – | – | – | – | – | – | – |
T7F | 1A2 | ND | ND | ND | ND | ND | ND | ND | ND | – | – | – | – | 11 | – | – | – |
T6a,b | 1C4 | – | 37 | – | – | – | – | – | 100 | – | – | – | 142 | – | – | – | – |
T6a, b | 1D7 | – | 355 | – | – | – | – | – | 334 | – | – | – | 2247 | – | – | – | – |