Skip to main content
Fig. 2 | BMC Infectious Diseases

Fig. 2

From: Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response

Fig. 2

S. pneumoniae serotype 4-specific mAb protects mice from S. pneumoniae serotype 4 challenge. a Survival rate of each treatment group at 96 h post-infection. Log-rank (Mantel-Cox) test was performed. Each group was compared to No Antibody Treatment Group. * p < 0.05, statistically significant difference. b Mean weight of survivors in each group at 0, 24, 48, 72 h post-infection. c Bacteremia of each animal at 48 h post-infection. Individual raw data plotted on Log10 scale with geometric mean and 95% CI. Transformed data analyzed by One-way ANOVA with Dunnett post test to evaluate for significant reduction in blood CFU counts (compared to No Antibody Treatment Group), *** p < 0.001, highly statistically significant difference

Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us