Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil

Table 1 Demographic variables distribution according with clinical condition of HAM/TSP patients

Variables	HAM/TSP	Asymptomatic	OR (CI:95%)	p-value	Corrected p-value^d
Skin color (n/%)
White	40 (46.5)	46 (53.5)	1
Non-White	28 (43.1)	37 (56.9)	0.87 (0.45–1.66)	0.67^a	1.00
Sex (n/%)
Male	27 (41.5)	38 (58.5)	1
Female	41 (47.7)	45 (52.3)	1.28 (0.67–2.47)	0.45^a	1.00
Age
Mean (SD)	57.8 (11.3)	53.3 (14.7)	1.03 (1–1.05)	0.04^b	0.16
PVL Median (IQR)	7.1(4.0–9.8)	1.3 (0–4.9)	1.14 (1.06–1.24)	< 0.01^c	< 0.04

HAM/TSP HTLV-1-associated myelopathy / Tropical spastic paraparesis, OR odds ratio, CI confidence interval, SD standard deviation, PVL proviral loads
^aChi-Square or Fisher Exact test. ^bT-test for comparison of difference means and ^cKruskal-Wallys test. ^dAdjusted p-value using Bonferroni correction for multiple comparisons

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