Catheter-associated bacterial flora in patients with benign prostatic hyperplasia: shift in antimicrobial susceptibility pattern

Table 3 Susceptibility to selected antibiotics or their combinations of bacterial flora in patients with benign prostatic hyperplasia and indwelling catheters

	1994–96	2004–06	2011–15	P value
No. of patients	169	132	156
No. of patients with bacteriuria	119 (70%)	95 (72%)	107 (69%)
Bacteriuria susceptible to:
Ciprofloxacin	76 (64%)*	34 (36%)*	30 (28%)	* < 0.001
Amikacin	102 (86%)*	55 (58%)*	61 (57%)	* < 0.0001
Amox/clav	ND	44 (46%)	44 (41%)	NS
Cefuroxime	51 (43%)*	22 (23%)*	28 (26%)	* < 0.01
Cotrimoxazole	12 (10%)*	27 (28%)*†	49 (46%)†	* < 0.001 † 0.01
Imipenem	ND	86 (90%)	102 (95%)	NS
Amikacin+Amox/clav	103 (87%)	79 (83%)	83 (77%)	NS
Imipenem+Vancomycin	ND	93 (98%)	104 (97%)	NS

Only when all strains isolated from a single patient were susceptible to one antibiotic or to a combination susceptibility in this analysis was recognized. When one or more strains were resistant, intermediate susceptible or not examined for a specific antibiotic non-susceptible status was given. Numbers and percentages of patients with susceptible flora relative to all patients with bacteriuria are reported
Amox/clav amoxicillin with clavulanic acid
The * or † character was used to determine which pair of values in the row was compared with a statistical test

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