Table 3 Network estimates of treatment success with 95% confidence intervals and GRADE assessments
Treatment comparison | Direct estimate; OR (95% CI) | quality of evidence | Indirect estimate; OR (95% CI) | quality of evidence | Network estimate; OR (95% CI) | quality of evidence |
|---|---|---|---|---|---|---|
ADV FTC | Not available | Not available | 0.02 (0.00–3.01) | Very low ⊕◯◯◯ | 0.02 (0.00–3.01) | Very low ⊕◯◯◯ |
ADV vs LMV | Not available | Not available | 0.07 (0.00–3.36) | Very low ⊕◯◯◯ | 0.07 (0.00–3.36) | Very low ⊕◯◯◯ |
ADV vs TD | Not available | Not available | 0.31 (0.02–6.28) | Very low ⊕◯◯◯ | 0.31 (0.02–6.28) | Very low ⊕◯◯◯S |
ADV vs TDF plus LMV | Not available | Not available | 0.18 (0.00–9.2) | Very low ⊕◯◯◯ | 0.18 (0.00–9.2) | Very low ⊕◯◯◯ |
ADV vs placebo | Not available | Not available | 0.05 (0.00–4.71) | Very low⊕◯◯◯ | 0.05 (0.00–4.71) | Very low ⊕◯◯◯ |
FTC vs LMV | Not available | Not available | 3.01 (0.03–287.25) | Very low ⊕◯◯◯ | 3.01 (0.03–287.25) | Very low ⊕◯◯◯ |
FTC vs TDF plus LMV | Not available | Not available | 7.82 (0.08–778.9) | Very low | 7.82 (0.08–778.9) | Very low |
FTC vs placebo | Not available | Not available | 2.23 (0.01–370.4) | Very low ⊕◯◯◯ | 2.23 (0.01–370.4) | Very low ⊕◯◯◯ |