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Table 2 Sample size and power calculations for different scenarios

From: Study protocol of the iMPaCT project: a longitudinal cohort study assessing psychological determinants, sexual behaviour and chlamydia (re)infections in heterosexual STI clinic visitors

 

Change (%)

Sample size needed at baseline (80% power)

Expected power with sample size n = 2000 at baseline

Ct+

Ct-

Ct + (n = 300)

Ct- (n = 1700)

Scenario 1

10%

470

611

60%

> 99%

Scenario 2

15%

220

286

91%

> 99%

Scenario 3

20%

129

167

> 99%

> 99%

  1. Sample size and power calculations to detect a change in psychological determinants or sexual behaviour at six-month follow-up with at least 80% power, assuming 34% loss to follow-up in the chlamydia positives (Ct+) and 55% loss to follow-up in the chlamydia negatives (Ct-)
  2. Abbreviations: Ct+ chlamydia positive, Ct- chlamydia negative