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Table 5 Univariate and multivariate analyzes the factors associated with ineffective viral suppression

From: Research on the treatment effects and drug resistances of long-term second-line antiretroviral therapy among HIV-infected patients from Henan Province in China

Predictor   OR(95%CI) p a OR(95%CI) p
Age(years) ≤45 1    
> 45 0.72(0.35,1.48) 0.367   
Gender Male 1    
Female 0.74(0.36,1.55) 0.431   
Education degree illiteracy 1    
Primary school 1.23(0.44,3.44) 0.699   
Junior middle school 0.91(0.30,2.72) 0.865   
Baseline CD4 + T cells/μl CD4 ≤ 50 2.86(0.64,12.7) 0.168 2.68(0.35,20.35) 0.340
50 < CD4 ≤ 200 1.63(0.77,3,47) 0.202 1.20(0.45,3.19) 0.450
CD4 > 200 1    
Baseline viral load copies/ml 1000 < HIV RNA ≤ 10,000 1   1  
10,000 < HIV RNA ≤ 10,000 1.31(0.52,3.31) 0.567 1.07(0.34,3.32) 0.914
HIV RNA > 100,000 3.46(1.27,9.37) 0.015 2.18(0.63,7.61) 0.221
Duration of first-line therapy (years) ≤4 1    
> 4 1.35(0.60,3.04) 0.475   
Baseline 3TC/TDF resistance sensitive 1   1  
low/moderate resistance 0.28(0.12,0.66) 0.004 0.29(0.10,0.83) 0.022
high resistance 0.16(0.05,0.49) 0.001 0.10(0.24,0.43) 0.002
medication adherence 90–100% 1   1  
< 90% 9.98(2.00,49.89) 0.005 22.74(3.38,152.59) 0.001
unknown 7.48(2.95,18.97) < 0.001 9.40(2.98,29.67) < 0.001
  1. 3TC Lamivudine, TDF Tenofovir