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Table 2 The genotype and allele frequencies of rs3764880 in patients with TB and controls

From: Association of TLR8 and TLR9 polymorphisms with tuberculosis in a Chinese Han population: a case-control study

Genotypes and allele frequencies

Cases, n (%)

Controls, n (%)

OR (95%CI)

P value

Males

 TLR8 rs3764880 major allele G

253 (86.6)

236 (79.5)

1

Reference

 TLR8 rs3764880 minor allele A

39 (13.4)

61 (20.5)

0.58 (0.37–0.91)

0.02

Females

 TLR8 rs3764880 GG

203 (71.2)

209 (68.8)

1

Reference

 TLR8 rs3764880 GA

76 (26.7)

82 (27.0)

0.93 (0.65–1.35)

0.71

 TLR8 rs3764880 AA

6 (2.1)

13 (4.3)

0.49 (0.18–1.31)

0.16

 TLR8 rs3764880 major allele G

482 (84.6)

500 (82.2)

1

Reference

 TLR8 rs3764880 minor allele A

88 (15.4)

108 (17.8)

0.84 (0.61–1.14)

0.26

  1. Abbreviations: TB tuberculosis, OR odds ratio, CI confidence interval. P value adjusted for age and smoking