Immunogenicity and safety of a tetanus-diphtheria vaccine and a 13-valent pneumococcal conjugate vaccine after concomitant vaccination in ≥ 50-year-old adults

Table 3 Comparison of geometric mean titers for opsonophagocytic activity (OPA) after 13-valent pneumococcal conjugate vaccine (PCV13) administration: PCV13 + tetanus-diphtheria (Td) versus PCV13 alone

Serotype	Group	Pre-vaccination OPA		p-value	Post-vaccination OPA		p-value
Serotype	Group	GMT	95% CI	p-value	GMT	95% CI	p-value
1	1	11	8–14	0.44	619	465–828	0.02
	2	10	7–12		392	304–506
5	1	7	6–9	0.09	1140	877–1479	0.45
	2	9	7–11		1312	1016–1690
18C	1	175	118–259	0.18	10,069	8933–11,350	0.28
	2	248	176–350		9078	7852–10,520
19A	1	417	303–574	0.40	1517	1349–1706	0.72
	2	346	257–467		1866	1675–2075

ISSN: 1471-2334