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Table 1 Baseline characteristics of the study population by origin, n = 726

From: Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study

Baseline Characteristics

Norwegian-born

Foreign-born

Total

p-value

Number of individuals

131 (100)

595 (100)

726 (100)

 

Gender

   

0.115

 Male

69 (53)

358 (60)

427 (59)

 

Age at notification

   

> 0.001

 < 5 years

37 (28)

25 (4)

62 (9)

 

 5–14 years

10 (8)

132 (22)

142 (20)

 

 15–34 years

33 (25)

315 (53)

348 (48)

 

 35–64 years

36 (27)

115 (19)

151 (21)

 

 > 65 years

15 (11)

8 (1)

23 (3)

 

Risk groupsa

Any risk factora

121(92)

342 (58)

463 (64)

 

Recent exposure, contacts

68 (52)

95 (16)

163 (22)

> 0.001

 Contacts < 5 years

35 (27)

3 (0.5)

38 (5)

 

Positive chest X-ray, any

7 (5)

60 (10)

67 (9)

0.090

 Fibrotic lesions

2 (2)

17 (3)

19 (3)

0.388

Immunosuppressive condition

51 (39)

72 (12)

123 (17)

> 0.001

 HIV infection

–

12 (2)

12 (2)

 

 Chronic renal disease

1 (1)

4 (1)

5 (1)

 

 Diabetes, any

1 (1)

4 (1)

5 (1)

 

 Underlying disease relevant for Immunosuppressive treatmentb

13 (10)

10 (2)

23 (3)

 

 Other medical conditionsc

36 (7)

42 (7)

78 (15)

 

Interferon Gamma Release Assay (IGRA)

   

> 0.001

 Positive

94 (72)

577 (97)

671 (92)

 

 Negative

15 (11)

5 (1)

20 (3)

 

 Inconclusive

2 (2)

–

2 (0)

 

 Missing or unknown

20 (15)

13 (2)

33 (5)

 

Regimen

   

> 0.001

 3RH dailyI

97 (74)

302 (51)

399 (55)

 

 3RPH weeklyII

30 (23)

276 (46)

306 (42)

 

 4R or 6H monotherapy dailyIII

3 (2)

15 (3)

18 (2)

 

 OtherIV

–

2 (0)

2 (0)

 

 Missing

1 (1)

–

1 (0)

 

TB IR (per 100,000) in country of birth#

 < 150

na

267 (45)

267 (45)

 

 150–200

na

127 (21)

127 (21)

 

 > 200

na

197 (33)

197 (33)

 

 Missing

na

4 (1)

4 (1)

 
  1. Data are presented as n (%) or median [interquartile range]. % refers to columns and not rows
  2. aAccording to Norwegian guidelines for the management and control of tuberculosis: with strong or conditional recommendation for LTBI treatment (age < 15 years, known exposure, positive chest X-ray or immunosuppressive condition)
  3. bIncludes rheumatologic-, dermatologic-, neurologic- and gastroenterological medical conditions
  4. cOther medical conditions include unspecified immunosuppressive conditions reported by the clinician
  5. I3RH: rifampicin (R) and isoniazid (H) daily for three months
  6. II3RPH: rifapentine (RP) and isoniazid (H) in 12 weekly doses
  7. IIIRifampicin (R) monotherapy daily for four months or isoniazid (H) monotherapy daily for six months
  8. IVOthers include full-course TB treatments for two individuals for two and four months respectively
  9. # Four immigrants had missing information on country of birth