Distribution of virulence genes and their association with antimicrobial resistance among uropathogenic Escherichia coli isolates from Iranian patients

Table 4 Distribution of virulence genes among UPEC isolates according to ESBL production

Gene	ESBL-negative	ESBL-positive	P value
Gene	Positive No. (%)		P value
pap GII	20 (35.1)	38 (55.1)	0.03
iutA	31 (54.4)	55 (79.7)	0.004
fimH	56 (98.2)	69 (100)	0.45
PAI	42 (73.7)	66 (95.7)	0.001
hlyA	15 (26.3)	21 (30.4)	0.69
sfa	42 (73.7)	58 (84.1)	0.19
afa	35 (61.4)	23 (33.3)	0.002

Abbreviations: UPEC = Uropathogenic Escherichia coli, ESBL = extended-spectrum β- lactamase, pap = pilus associated with pyelonephritis, iutA = iron uptake transfer (ferric aerobactin receptor), fimH = type-1 fimbriae, PAI = pathogenicity-associated island, hlyA = hemolysin, sfa = S-fimbriae, afa = afimbrial adhesin)