From: High dose fluconazole in salvage therapy for HIV-uninfected cryptococcal meningitis
Variables | No. (%) of patients |
---|---|
Sex, male | 28 (63.6) |
Age, years | 44 (range, 16–73) |
Predisposing factors | |
Evans syndrome | 4 (9.1) |
MDS | 1 (2.3) |
ITP | 1 (2.3) |
Lymphoma | 1 (2.3) |
Solid tumora | 2 (4.5) |
SLE | 5 (11.4) |
Cirrhosis | 2 (4.5) |
Liver transplantation | 1 (2.3) |
Splenectomy | 1 (2.3) |
Type 2 diabetes mellitus | 2 (4.5) |
Steroids or immunosuppressants | 10 (22.7) |
Headache | 44 (100) |
Fever | 32 (72.7) |
Vomiting | 32 (72.7) |
Meningeal irritation | 32 (72.7) |
Seizure | 16 (36.4) |
Altered mental statusb | 12 (27.3) |
Cranial nerve defect | |
Impaired vision | 16 (36.4) |
Diplopia | 8 (18.2) |
Visual field defect | 8 (18.2) |
Ophthalmodynia | 3 (6.8) |
Hearing impairment | 18 (40.9) |
Facial paralysis | 3 (6.8) |
Limb weakness | 14 (31.8) |
uracratia | 3 (6.8) |
Dysuria | 3 (6.8) |