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Table 1 Clinical characteristic on admission of patients with bloodstream infection

From: Clinical characteristics, organ failure, inflammatory markers and prediction of mortality in patients with community acquired bloodstream infection

Factor

Proportion

Case fatality rate

Unadjusted odds ratios (95%CI) for case fatality

P values

Age (yrs)

  ≤ 40 years old

122/393 (31%)

27 (22.1%)

1

 

 41–55 years old

152/393 (38.7%)

46 (30.3%)

1.527 (0.881–2.646)

0.131

  ≥ 56 years old

119/393 (30.3%)

37 (31.1%)_

1.588 (0.891–2.828)

0.117

Male sex (%)

271/393 (69.0%)

84 (31.0%)

1.659 (1.002–2.746)

0.049

Any previous hospitalisation (%)

150/393 (38.2%)

62 (41.3%)

2.862 (1.819–4.503)

< 0.001

Any antibiotic prior to NHTD hospitalisation (%)

50/150 (33.3%)

23 (46.0%)

1.332 (0.671–2.646)

0.412

Time from onset to current hospitalisation < 5 days

217/393 (55.2%)

57 (26.3%)

0.827 (0.532–1.286)

0.399

Direct ICU admission

145/393 (36.9%)

68 (46.9%)

4.331 (2.720–6.898)

< 0.001

Any history of medical disease

106/393 (27.0%)

44 (41.5%)

2.376 (1.479–3.818)

< 0.001

 HIV

19/393 (4.8%)

10 (52.6%)

3.044 (1.202–7.710)

0.019

 Moderate or severe liver disease

53/393 (13.5%)

25 (47.2%)

2.679 (1.481–4.844)

0.001

 Diabetes

25/393 (6.4%)

7 (28.0%)

1.001 (0.406–2.466)

0.999

Concurrent foci of infection

 Radiology-confirmed pneumonia on admission

98/393 (24.9%)a

29 (29.6%)

1.11 (0.671–1.837)

0.684

 Lumbar puncture confirmed meningitis on admission

72/393 (18.3%)b

19 (26.4%)

0.906 (0.509–1.614)

0.738

 Heart valve vegetations during hospitalisation

16/393 (4.1%)

4 (25.0%)

0.852 (0.269–2.701)

0.786

 Any abscess during hospitalisation

33/393 (8.4%)c

6 (18.2%)

0.547 (0.219–1.364)

0.196

Organ dysfunction on admission

 Cardiovascular

65/393 (16.5%)

52 (80.0%)

18.621 (9.522–36.415)

< 0.001

 Respiratory

87/393 (22.1%)

53 (60.9%)

6.81 (4.057–11.431)

< 0.001

 CNS

105/393 (26.7%)

55 (52.4%)

4.66 (2.876–7.551)

< 0.001

 Hepatic

146/393 (37.2%)

57 (39.0%)

2.344 (1.494–3.678)

< 0.001

 Renal

153/393 (38.9%)

66 (43.1%)

3.379 (2.139–5.339)

< 0.001

 Coagulation

226/393 (57.5%)

85 (37.6%)

3.424 (2.070–5.663)

< 0.001

  1. aIsolates from blood in patients with pneumonia were K. pneumoniae (22.4%, 22/98), E. coli (16.3%, 16/98), S. maltophilia (11.2%, 11/98), Burkholderia pseudomallei (8.2%, 8/98), S. aureus (7.1%, 7/98) and S. suis (7.1%, 7/98) and other pathogens (23.5%, 27/98)
  2. bIsolates from blood in patients with meningitis were S. suis (40/72, 55.6%), K. pneumoniae (8/72, 11.1%), Stenotrophomonas maltophilia (7/72, 9.7%), S. aureus (5/72, 6.9%). Enterococcus species (2/72, 2.8%), Listeria species (2/72, 2.8%), E. coli (2/72, 2,8%), Salmonella enterica (2/72,2.8%) and each of S. pneumoniae, beta hemolytic Streptococcus, viridans group Streptococcus and Enterobacter species (1/72, 1.4%)
  3. cThere were 16 cases with liver abscess with isolates from blood were K. pneumoniae (8/16 or 50%), E. coli and Salmonella enterica (2/16 of each, or 12.5%), Aeromonas species, Enterobacter species, S. suis and viridans group streptococci (1/16 of each, 6.3%)