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Table 1 Clinical characteristic on admission of patients with bloodstream infection

From: Clinical characteristics, organ failure, inflammatory markers and prediction of mortality in patients with community acquired bloodstream infection

Factor Proportion Case fatality rate Unadjusted odds ratios (95%CI) for case fatality P values
Age (yrs)
  ≤ 40 years old 122/393 (31%) 27 (22.1%) 1  
 41–55 years old 152/393 (38.7%) 46 (30.3%) 1.527 (0.881–2.646) 0.131
  ≥ 56 years old 119/393 (30.3%) 37 (31.1%)_ 1.588 (0.891–2.828) 0.117
Male sex (%) 271/393 (69.0%) 84 (31.0%) 1.659 (1.002–2.746) 0.049
Any previous hospitalisation (%) 150/393 (38.2%) 62 (41.3%) 2.862 (1.819–4.503) < 0.001
Any antibiotic prior to NHTD hospitalisation (%) 50/150 (33.3%) 23 (46.0%) 1.332 (0.671–2.646) 0.412
Time from onset to current hospitalisation < 5 days 217/393 (55.2%) 57 (26.3%) 0.827 (0.532–1.286) 0.399
Direct ICU admission 145/393 (36.9%) 68 (46.9%) 4.331 (2.720–6.898) < 0.001
Any history of medical disease 106/393 (27.0%) 44 (41.5%) 2.376 (1.479–3.818) < 0.001
 HIV 19/393 (4.8%) 10 (52.6%) 3.044 (1.202–7.710) 0.019
 Moderate or severe liver disease 53/393 (13.5%) 25 (47.2%) 2.679 (1.481–4.844) 0.001
 Diabetes 25/393 (6.4%) 7 (28.0%) 1.001 (0.406–2.466) 0.999
Concurrent foci of infection
 Radiology-confirmed pneumonia on admission 98/393 (24.9%)a 29 (29.6%) 1.11 (0.671–1.837) 0.684
 Lumbar puncture confirmed meningitis on admission 72/393 (18.3%)b 19 (26.4%) 0.906 (0.509–1.614) 0.738
 Heart valve vegetations during hospitalisation 16/393 (4.1%) 4 (25.0%) 0.852 (0.269–2.701) 0.786
 Any abscess during hospitalisation 33/393 (8.4%)c 6 (18.2%) 0.547 (0.219–1.364) 0.196
Organ dysfunction on admission
 Cardiovascular 65/393 (16.5%) 52 (80.0%) 18.621 (9.522–36.415) < 0.001
 Respiratory 87/393 (22.1%) 53 (60.9%) 6.81 (4.057–11.431) < 0.001
 CNS 105/393 (26.7%) 55 (52.4%) 4.66 (2.876–7.551) < 0.001
 Hepatic 146/393 (37.2%) 57 (39.0%) 2.344 (1.494–3.678) < 0.001
 Renal 153/393 (38.9%) 66 (43.1%) 3.379 (2.139–5.339) < 0.001
 Coagulation 226/393 (57.5%) 85 (37.6%) 3.424 (2.070–5.663) < 0.001
  1. aIsolates from blood in patients with pneumonia were K. pneumoniae (22.4%, 22/98), E. coli (16.3%, 16/98), S. maltophilia (11.2%, 11/98), Burkholderia pseudomallei (8.2%, 8/98), S. aureus (7.1%, 7/98) and S. suis (7.1%, 7/98) and other pathogens (23.5%, 27/98)
  2. bIsolates from blood in patients with meningitis were S. suis (40/72, 55.6%), K. pneumoniae (8/72, 11.1%), Stenotrophomonas maltophilia (7/72, 9.7%), S. aureus (5/72, 6.9%). Enterococcus species (2/72, 2.8%), Listeria species (2/72, 2.8%), E. coli (2/72, 2,8%), Salmonella enterica (2/72,2.8%) and each of S. pneumoniae, beta hemolytic Streptococcus, viridans group Streptococcus and Enterobacter species (1/72, 1.4%)
  3. cThere were 16 cases with liver abscess with isolates from blood were K. pneumoniae (8/16 or 50%), E. coli and Salmonella enterica (2/16 of each, or 12.5%), Aeromonas species, Enterobacter species, S. suis and viridans group streptococci (1/16 of each, 6.3%)