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Table 5 HI-titer in relation to risk of pre-eclampsia, preterm birth, small for gestational age birth, and birth weight

From: Risk of pregnancy complications and adverse birth outcomes after maternal A(H1N1)pdm09 influenza: a Norwegian population-based cohort study

 

HI-titer = 5, n = 575

HI-titer ≥10, n = 201

Pre-eclampsia

 Cases, n (%)

16 (2.8)

5 (2.5)

 Crude OR (95% CI)

1 (Ref)

0.89 (0.32, 2.46)

 Adjusted OR (95% CI)a

1 (Ref)

0.83 (0.29, 2.36)

Preterm birth

 Cases, n (%)

13 (2.3)

6 (3.0)

 Crude OR (95% CI)

1 (Ref)

1.33 (0.50, 3.55)

 Adjusted OR (95% CI)a

1 (Ref)

1.26 (0.47, 3.40)

Small for gestational age birth

 Cases, n (%)

45 (7.8)

20 (10.0)

 Crude OR (95% CI)

1 (Ref)

1.30 (0.75, 2.26)

 Adjusted OR (95% CI)a

1 (Ref)

1.30 (0.74, 2.81)

Birth weight

 10th percentile (g)

3000

2932

 Difference in 10th percentile, β (95% CI)b

1 (Ref)

−123 (−248, 2)

 50th percentile (g)

3560

3580

 Difference in 50th percentile, β (95% CI)b

1 (Ref)

−10 (− 97, 76)

  1. aLogistic regression adjusted for maternal age at birth (continuous), parity (primiparous/multiparous), smoking during pregnancy (yes/no), and time in days between birth and pandemic (continuous). The model was also adjusted for influenza risk group (yes/no) except with pre-eclampsia as the outcome
  2. bQuantile regression adjusted for maternal age at birth (continuous), parity (primiparous/multiparous), smoking during pregnancy (yes/no), influenza risk group (yes/no), and time in days between birth and pandemic (continuous)