Pathogen-specific parameters
| | | | | | |
1/γ: Infectious
|
6
|
[38–40]
|
10.4
|
[41]
|
15
|
[42]
|
period (days)
| | | | | | |
α: Shedding rate (pathogen hours −1 people −1)
|
1×104
|
[43–45]
|
1×103
|
[46, 47]
|
2.88×103
|
[48, 49]
|
μF: Inactivation rate
|
0.121
|
[50–52]
|
1.44
|
[53, 54]
|
0.288
|
[8]
|
in fomites (hours −1)
|
(0.058, 0.121)
|
(0.990, 1.44)
|
(0.0006, 0.288)
|
μH: Inactivation rate
|
88.2
|
[13, 50, 52]
|
0.767
|
[55]
|
1.07
|
[9, 56, 57]
|
in hands (hours −1)
|
(55.2, 88.2)
| |
(0, 1.07)
|
τFH: Transfer
|
0.1
|
[13, 16, 50, 58]
|
0.2
|
[55, 59–61]
|
0.07
|
[62]
|
efficacy (F to H) (proportion)
|
(0.04, 0.16)
|
(0.1, 0.40)
|
(0.051, 0.089)
|
τHF: Transfer
|
0.025
|
[13, 16, 50, 58]
|
0.2
|
[55, 59–61]
|
0.13
|
[62]
|
efficacy (H to F) (proportion)
|
(0.01, 0.04)
|
(0.1, 0.40)
|
(0.094, 0.166)
|
ϕH: Pathogen
|
0.15
| |
0.15
| |
0.90
| |
excreted to H (proportion)
|
(0.10, 0.2)
|
(0.10, 0.2)
|
(0.50, 1)
|
ϕF: Pathogen
|
1−ϕH
|
1−ϕH
|
1−ϕH
|
excreted to F (proportion)
| | | | | | |
π:Infectivity parameter in contact
| |
with x pathogens (unitless) a
|
6.93e-05
|
2.46e-3
|
4.78e-4
|
aH: rate pathogens are added to hands
|
α
ϕ
H
|
α
ϕ
H
|
α
ϕ
H
|
(pathogen time −1 people −1)
| | | | | | |
Venue-specific parameters
| | | | | | |
λ: Accessible surfaces (proportion)
|
(0, 0.6)
|
(0, 0.6)
|
(0, 0.6)
|
κ: fingertip to surface ratio per individual
|
\(\frac {6e-06}{\lambda }\)
|
\(\frac {6e-06}{\lambda }\)
|
\(\frac {6e-06}{\lambda }\)
|
(1/people) b
| | | | | | |
ρT: Rate of fomite touching (days −1)
|
(0, 60)
|
(0, 60)
|
(0, 60)
|
ρFH: rate of pathogen pick up from fomites to hand
|
ρ
T
τ
FH
κ
|
ρ
T
τ
FH
κ
|
ρ
T
τ
FH
κ
|
1/(days × people)
| | | | | | |
ρFH: rate of pathogen deposit from hand to fomite
|
ρ
T
τ
HF
|
ρ
T
τ
HF
|
ρ
T
τ
HF
|
1/(days × people)
| | | | | | |
aF: rate pathogens are added to fomites
|
α
ϕ
F
λ
|
α
ϕ
F
λ
|
α
ϕ
F
λ
|
(pathogen days −1 people −1)
| | | | | | |
Cleaning parameters
| | | | |
ΘF: Rate of fomite cleaning (days −1)
|
(0, 2)
|
(0, 2)
|
(0, 2)
|
ΘH: Rate of hand cleaning (days −1)
|
(0, 3)
|
(0, 3)
|
(0, 3)
|
qF: Fomite cleaning efficacy (proportion)
|
1
|
1
|
1
|
qH: Hand cleaning efficacy (proportion)
|
1
|
1
|
1
|
θF: Effective fomite cleaning rate
|
q
F
Θ
F
|
q
F
Θ
F
|
q
F
Θ
F
|
θH: Effective hand cleaning rate
|
q
H
Θ
H
|
q
H
Θ
H
|
q
H
Θ
H
|
Fixed parameters (across pathogens
| | | |
and venues)
| |
ρ: Inoculation (hours −1)
|
15.8
|
[23, 24]
|
15.8
|
[23, 24]
|
15.8
|
[23, 24]
|
χ: proportion of pathogens absorbed when
|
1
|
1
|
1
|
self-inoculation occurs (proportion)
| | | | | | |
a Parameter fixed based on linearization of the dose-response curve
|
b Parameter fixed based on relative finger to body size.
|