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Table 3 Meta-analysis of each secondary outcome

From: Efficacy and safety of cefazolin versus antistaphylococcal penicillins for the treatment of methicillin-susceptible Staphylococcus aureus bacteremia: a systematic review and meta-analysis

Outcome No. of studies No. of patients OR (95% CI) P Value I2% Effects model
Clinical failure 5 778 0.56 (0.37–0.85) 0.12 44.9 Fixed
Recurrence of bacteremia 8 4017 1.12 (0.94–1.34) 0.80 0 Fixed
AEs 5 672 0.37 (0.10–1.41) 0 83.1 Random
Hepatotoxicity 4 645 0.12 (0.04–0.41) 0.51 0 Fixed
Nephrotoxicity 3 484 0.36 (0.16–0.81) 0.88 0 Fixed
Anaphylaxis 5 672 0.91 (0.36–2.99) 0.53 0 Fixed
Hematotoxicity 4 511 0.56 (0.17–1.88) 0.42 0 Fixed
Discontinuation due to AEs 3 468 0.24 (0.12–0.48) 0.30 18 Fixed
  1. AEs adverse effects, CI confidence interval, OR odds ratio