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Table 1 Risk factors analysis of patients with P. aeruginosa SSI and SSI due other organisms

From: Preoperative oral antibiotic prophylaxis reduces Pseudomonas aeruginosa surgical site infections after elective colorectal surgery: a multicenter prospective cohort study

Epidemiological characteristics

Non-SSI

(n = 3032)

P. aeruginosa SSI (n = 62)

Other SSI

(n = 607)

*P-value

OR (95% CI)

Age, median (IQR), years

69.6 (60.7–78)

71.3 (64.9–80)

69.9 (61.4–77)

0.1

1.0 (0.97–1.12)

Male sex, n (%)

1814 (59.8)

44 (71)

431 (71)

0.9

1.0 (0.56–1.78)

ASA III-IV, n (%)

1178 (38.9)

42 (67.7)

276 (45.5)

0.001

2.5 (1.44–4.39)

NNIS 1–2, n (%)

993 (32.8)

46 (74.2)

268 (44.2)

< 0.001

3.6 (2.01–6.56)

Indication for surgery, n (%):

 - Neoplasia

2868 (94.6)

57 (91.9)

577 (95.1)

0.3

0.5 (0.22–1.58)

 - Inflammatory bowel disease

73 (2.4)

3 (4.8)

15 (2.5)

0.3

2.0 (0.56–7.13)

 - Other

87 (2.9)

2 (3.2)

14 (2.3)

0.6

1.4 (0.31–6.36)

Type of surgery, n (%)

   

0.2

1.3 (0.81–2.33)

 - Colon

2104 (69.4)

34 (54.8)

380 (62.6)

  

 - Rectum

928 (30.6)

28 (45.2)

227 (37.4)

  

Adequate antibiotic prophylaxis, n (%)

2526 (83.3)

55 (88.7)

502 (82.7)

0.2

1.6 (0.73–3.37)

Duration of surgery ≥75th pa, n (%)

1163 (38.4)

38 (61.3)

251 (41.4)

0.003

2.2 (1.31–3.83)

Laparoscopic surgery, n (%)

1975 (65.1)

25 (40.3)

297 (48.9)

0.2

0.7 (0.41–1.29)

Detection of SSI during hospitalization, n (%)

_

46 (74.2)

435 (71.7)

0.6

1.1 (0.65–1.93)

Oral antibiotic prophylaxis, n (%)

1352 (44.6)

11 (17.7)

204 (33.6)

0.01

0.4 (0.21–0.83)

Mechanical bowel preparation, n (%)

2283 (77.1)

50 (80.6)

454 (75.8)

0.4

1.3 (0.69–2.56)

Ostomy, n (%)

715 (23.6)

29 (46.8)

218 (36)

0.09

1.5 (0.92–2.64)

Previous chemotherapy, n (%)

471 (15.5)

15 (24.2)

125 (20.6)

0.5

1.2 (0.66–2.26)

Previous radiotherapy, n (%)

452 (14.9)

14 (22.6)

112 (18.5)

0.4

1.3 (0.68–2.41)

Type of SSI, n (%):

   

0.6

1.1 (0.67–1.92)

 - Incisional

_

29 (46.8)

304 (50.1)

  

 - Organ-space

_

33 (53.2)

303 (49.9)

  
  1. P. aeruginosa: Pseudomonas aeruginosa, SSI: surgical site infection, IQR: interquartile range, ASA: American Society of Anaesthesiologists’ physical status, NNIS: National Nosocomial Infections Surveillance Risk Index
  2. *P-value refers to comparison between P. aeruginosa SSI and other SSI
  3. aLength of surgery greater than the 75th percentile of the procedure