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Table 1 Characteristics of IDU-IE and non-IDU-IE at UVA from January 2000 to July 2016

From: Rising rates of injection drug use associated infective endocarditis in Virginia with missed opportunities for addiction treatment referral: a retrospective cohort study

Demographic factors

IDU-IE, N = 76

Non-IDU-IE N = 143

p-value

N (%)

N (%)

Sex

0.7

 Male

86 (60.8)

44 (57.9)

 

 Female

55 (39.2)

32 (42.1)

 

Race

0.02

 Caucasian

73 (96.1)

120 (84.7)

 

 Black

2 (2.6)

21 (14.8)

 

 Hispanic

1 (1.3)

1 (0.5)

 

Mean Age (range)

35 (19–63)

61 (12–89)

< 0.001

Residents of rural counties

24 (31.6)

45 (32.1)

0.9

In-hospital mortality

6 (7.9)

23 (16.6)

0.08

30 day mortalitya

9 (14.5)

31 (24.4)

0.1

90 day mortalitya

12 (21.8)

36 (29.3)

0.3

Insurance

< 0.0005

 Medicaid

22 (28.9)

11 (7.7)

 

 Medicare

10 (13.2)

87 (60.8)

 

 Private

7 (9.2)

28 (19.6)

 

 Uninsured

34 (44.7)

10 (7)

 

 Tricare (Federally funded)

0 (0)

1 (0.7)

 

 State and Local Hospitalization Program

2 (2.6)

2 (1.4)

 

 Other

1 (1.3)

4 (1.8)

 

Pathogen

< 0.0005

 MRSA

29 (38.2)

33 (23.5)

 

 MSSA

17 (22.4)

18 (12.5)

 

 Other staphylococci

0

7 (4.6)

 

Enteroccus faecalis

4 (5.3)

19 (13.1)

 

 Other enterococci

0

5 (3.8)

 

 Streptococci

7 (9.2)

35 (24.8)

 

 Candida species

3 (3.9)

6 (4.1)

 

 Polymicrobial infection

8 (10.5)

0

 

 Other

4 (5.3)

12 (8.3)

 

 No pathogen identified

4 (5.3)

7 (5.2)

 
 

Median (IQR)

Median (IQR)

p-valueb

Length of stay in days

17 (10–29)

10 (6–18)

0.001

ICU length of stay in days (n = 44)c

6 (2–12)

5 (2–8)

0.8

Hospital cost in dollars

47,899 (24,578–78,144)

26,460 (10,220–60,059)

0.001

  1. MSSA methicillin susceptible Staphylococcus aureus, MRSA methicillin resistant Staphylococcus aureus, ICU intensive care unit
  2. All data were adjusted for sampling weights
  3. aExcluding patients with missing mortality data: 14 patients with IDU-IE and 16 patients with non-I DU-IE for 30 day mortality and 21 patients with IDU-IE and 20 with non-IDU-IE for 90 day mortality
  4. bp-value from Mann-Whitney non-parametric test, other p-values from chi-squared test
  5. cExcluding 80% of patients with no ICU stay (IDU-IE = 58, non-IDU-IE = 117)