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Table 1 Demographic and clinical characteristics of study participants

From: Virologic suppression in response to antiretroviral therapy despite extensive resistance within HIV-1 reverse transcriptase after the first virologic failure

Variables

N

%

Age (years) (mean ± SD)

41,1 ± 9,4

 

Gender

 Male

135

73,4

 Female

49

26,6

Baseline CD4 count, median (Q1; Q3)

234, 0 (118, 0; 361, 0)

 

CD4

  < 200

78

42,4

 200 a 350

50

27,2

  > 350

47

25,5

 Data unavailable

9

4,9

VL (copies/ml), median (Q1; Q3)

19.812,5 (7.036,0; 78.674,2)

VL (copies/ml)

  ≤ 10.000

59

32,1

  > 10.000 a 100.000

75

40,7

  > 100.000

37

20,1

 Data unavailable

13

7,1

∆t on ART (months), median (Q1;Q3)

54, 5 (29, 0; 90, 0)

 

Δt in virologic failure

(months), median (Q1;Q3)

17, 0 (10, 0; 34, 0)

 

NRTI in failing regimen

184

100,0

 AZT/3TC

126

68,5

 TDF/3TC

48

26,1

 Others

10

5,4

NNRTI in failing regimen

155

84,2

 EFV

135

87,1

 NVP

20

12,9

PI in failing regimen

29

15,8

 LPV/r

16

55,2

 ATV/r ou ATV 400 mg

12

41,4

 Outros

1

3,4

Viral Subtype

171

92,9

 B

139

81,3

 F

31

18,1

 BF

1

0,4

  1. VL = viral load, ART antiretroviral therapy, NNRTIs nonnucleoside reverse transcriptase inhibitors, NRTIs nucleoside/nucleotide reverse transcriptase inhibitors, AZT zidovudine; 3TC lamivudine, TDF tenofovir, EFV: efavirenz, NVP nevirapine, PI protease inhibitor; LPV/r lopinavir/ritonavir, ATV/r atazanavir/ritonavir