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Table 1 Demographic variables and baseline clinical features (n = 219)

From: Factors affecting clinical outcomes in the management of melioidosis in Singapore: a 16-year case series

Variable

Frequency (%) / Mean ± SD

Demographics

 Gender

  Male

182 (83.1)

  Female

37 (16.9)

 Age (years)

55.7 ± 14.3

 Chinese

141 (64.4)

 Singapore resident

210 (95.9)

 Smoker

97 (44.3)

Comorbidities

 Diabetes mellitus

138 (63)

 Hypertension

97 (44.3)

 Hyperlipidemia

67 (30.6)

 Ischemic heart disease

39 (17.8)

 Lung disease

17 (7.8)

 Liver disease

11 (5)

 Renal disease

31 (14.2)

 Malignancies

22 (10)

 Rheumatological disease

12 (5.5)

 HIV infection

1 (0.5)

 Haematological condition

15 (6.8)

 Stroke

11 (5)

 History of tuberculosis

16 (7.3)

 History of melioidosis

11 (5)

 Immunosuppressive drugs

7 (3.2)

Symptoms

 Fever

178 (81.3)

 Chills or rigors

109 (49.8)

 Lethargy

106 (48.4)

 Cough

111 (50.7)

 Weight loss

62 (28.3)

 Urinary symptoms

43 (19.6)

 Joint pain or swelling

23 (10.5)

Total Duration of symptoms

 Less than 4 weeks

157 (71.7)

Disease Severity

 Bacteremia

148 (67.6)

 Multifocal infection

109 (49.8)

 Shock requiring inotropic support

46 (21)

 Acute kidney injury requiring dialysis

24 (11)

 Mechanical ventilation

47 (21.5)

Organ involvement

 Endovascular system

4 (1.8)

 Lung

156 (71.2)

 Liver

29 (13.2)

 Splenic

42 (19.2)

 Liver and spleen

13 (5.9)

 Genitourinary tract

52 (23.7)

 Musculoskeletal or SSTI

68 (31.1)

 Central nervous system

16 (7.3)

 Lymphatic system

60 (27.4)