Table 3 Sex-stratified prevalence of laboratory-confirmed genital tract infections (GTIs) among sexually experienced, non-pregnant South African youth (aged 16–24 years) enrolled in the AYAZAZI study, overall and by study site (n = 352)
Laboratory-confirmed infections | Durban | Soweto | Whole cohort | ||||||
|---|---|---|---|---|---|---|---|---|---|
Female n = 96 | Male n = 83 | Total n = 179 | Female n = 102 | Male n = 71 | Total n = 173 | Female n = 198 | Male n = 154 | Total n = 352 | |
≥ 1 GTI (excluding HIV) | 66 (68.8) | 10 (12.0) | 76 (42.5) | 73 (71.6) | 6 (8.5) | 79 (45.7) | 139 (70.2)* | 16 (10.4)* | 155 (44.0) |
Non-ulcerative STIs | |||||||||
C. trachomatis (CT) | 14 (14.6) | 7 (8.4) | 21 (11.7) | 22 (21.6) | 5 (7.0) | 27 (15.6) | 36 (18.2)* | 12 (7.8)* | 48 (13.6) |
N. gonorrhoeae (NG) | 5 (5.2) | 2 (2.4) | 7 (3.9) | 9 (8.8) | 0 (0) | 9 (5.2) | 14 (7.1)* | 2 (1.3)* | 16 (4.6) |
M. genitalium (MG) | 5 (5.2) | 3 (3.6) | 8 (4.5) | 14 (13.7) | 2 (2.8) | 16 (9.3) | 19 (9.6)* | 5 (3.3)* | 24 (6.8) |
T. vaginalis (TV) | 3 (3.1) | 0 (0) | 3 (1.7) | 13 (12.8) | 1 (1.4) | 14 (8.1) | 16 (8.1)* | 1 (0.7)* | 17 (4.8) |
≥ 1 of CT/NG/MG | 22 (22.9) | 10 (12.0) | 32 (17.9) | 38 (37.3) | 5 (7.0) | 43 (24.9) | 60 (30.3)* | 15 (9.7)* | 75 (21.3) |
≥ 1 non-ulcerative STI | 24 (25.0) | 10 (12.0) | 34 (19.0) | 45 (44.1) | 6 (8.5) | 51 (29.5) | 69 (34.8)* | 16 (10.4)* | 85 (24.1) |
Female-only GTIs | |||||||||
Bacterial Vaginosis (BV) | 52 (54.2) | 53 (52.0) | 105 (53.0) | ||||||
C. albicans (CA) | 7 (7.3) | 12 (11.8) | 19 (9.6) | ||||||
Co-infection | |||||||||
≥ 2 non-ulcerative STIs | 3 (3.1) | 2 (2.4) | 5 (2.8) | 11 (10.8) | 2 (2.8) | 13 (7.5) | 14 (7.0)* | 4 (2.6)* | 18 (5.0) |
≥ 1 non-ulcerative STI & ≥1 GTI | 16 (16.7) | 34 (33.3) | 50 (25.3) | ||||||
Among those with ≥ 1 non-ulcerative STI | |||||||||
≥ 2 non-ulcerative STIs | 3 (12.5) | 2 (20.0) | 5 (14.7) | 11 (24.4) | 2 (33.3) | 13 (25.5) | 14 (20.3) | 4 (25.0) | 18 (21.2) |
≥ 1 non-ulcerative STI & ≥1 GTI | 16 (66.7) | 34 (75.6) | 50 (72.5) | ||||||
Ulcerative STIs (among those with genital ulcers)a | n = 1 | n = 0 | n = 1 | n = 1 | n = 1 | n = 2 | n = 2 | n = 1 | n = 3 |
HSV-2 | 1 (100.0) | 0 (0) | 1 (100.0) | 0 (0) | 0 (0) | 0 (0) | 1 (50.0) | 0 (0) | 1 (33.3) |
T. pallidum | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
H. ducreyi | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
LGV | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
HIVb | 9 (9.4) | 2 (2.4) | 11 (6.2) | 1 (1.0) | 1 (1.4) | 2 (1.2) | 10 (5.1) | 3 (2.0) | 13 (3.7) |