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Table 4 Treatment Related Factors Associated with Virological Failure among Adolescents on ART in Harare City, 2017

From: Virological failure among adolescents on ART, Harare City, 2017- a case-control study

Variable

Category

Cases (%)

Controls (%)

OR

95%CI

Being on other medication

Yes

10 (10)

7 (7)

1.48

0.54–4.04

No

92 (90)

95 (93)

  

WHO staging

3&4

60 (59)

32 (33)

3.13

1.76–5.55

1&2

42 (41)

70 (67)

  

CD4 count

≤350

87 (85)

56 (55)

4.76

2.43–9.33

> 350

15 (15)

46 (45)

  

Duration on ART

≤18 months

84(82)

86(84)

0.87

0.41–1.82

> 18 months

18(18)

16(16)

Chronic illness

Yes

15 (15)

6 (6)

2.76

1.02–7.42

No

87(15)

96 (92)

  

Drug S/E

Yes

18 (18)

12 (12)

1.61

0.73–3.53

No

84 (82)

90 (88)

  

Having no history of OIs

Yes

63(62)

70(69)

0.67

0.38–1.21

No

39(38)

32(31)

  

TDF + 3TC + EFV

Yes

19(19)

38(37)

0.34

0.20–0.73

No

83(81)

64(63)

  

Being on 2nd line treatment

Yes

26 (25)

5 (5)

0.15

0.06–0.4

No

76 (75)

97 (95)