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Table 1 Patient characteristics in relation to hospital mortality

From: Impact of microbial Aetiology on mortality in severe community-acquired pneumonia

Characteristics All patients (n = 117) Survivors (n = 101) Non-survivors (n = 16) p-value
Demographics
 Age, years 62.5 ± 16.1 61.6 ± 16.5 68.5 ± 11.7 0.11
 Male 73 (62.4) 62 (61.4) 11 (68.8) 0.78
Comorbid illness
 Diabetes Mellitus 36 (30.8) 31 (30.7) 5 (31.3) 0.96
 Hypertension 67 (57.3) 58 (57.4) 9 (56.3) 0.93
 Cardiac disease 26 (22.2) 20 (19.8) 6 (37.5) 0.11
 Chronic lung disease 23 (19.7) 22 (21.8) 1 (6.3) 0.19
 Cerebrovascular disease 14 (12.0) 11 (10.9) 3 (18.8) 0.41
 Chronic liver disease 1 (0.9) 0 (0) 1 (0.06) 0.14
 End-stage renal failure 5 (4.3) 3 (3.0) 2 (12.5) 0.14
Symptoms
 Fever 71 (60.7) 63 (62.4) 8 (50) 0.35
 Cough 97 (82.9) 84 (83.2) 13(81.3) 0.85
 Purulent Sputum 63 (53.9) 57 (56.5) 6 (37.5) 0.16
 Dypsnea 82 (70.1) 70 (69.3) 12 (75.0) 0.65
Radiological features
 Localised lung infiltrates 35 (29.9) 30 (29.7) 5 (31.2) 0.90
 Multi-lobar lung infiltrates 82 (70.1) 71 (70.3) 11 (68.8) 0.90
 Pleural effusion 15 (12.8) 12 (11.9) 3 (18.8) 0.43
Laboratory Indices
 Serum C- reactive proteina (mg/L) 157.2 ± 114.8 157.9 ± 118.3 152.9 ± 93.9 0.87
 Serum procalcitoninb (ug/L) 19.8 ± 34.6 17.0 ± 32.3 38.4 ± 44.5 0.025
Microbiological factors
 Number of co-existent pathogens
  -0 33 (28.2) 30 (29.7) 3 (18.8) 0.010
  -1 64 (54.7) 58 (57.4) 6 (37.5)  
  -2 or more 20 (17.1) 13 (12.9) 7 (43.8)  
 Microbial aetiologies
  - No identified pathogen 33 (28.2) 30 (29.7) 3 (18.8) 0.008
  - Only bacterial pathogens present 27 (23.1) 26 (25.7) 1 (6.3)  
  - Only viral pathogens present 32 (27.4) 27 (26.7) 5 (31.3)  
  - Mixed viral-bacterial infection 18 (15.4) 11 (10.9) 7 (43.8)  
  - Atypical pathogens 7 (6.0) 7 (6.9) 0 (0)  
  Appropriate empirical antibiotics 108 (92.3) 94 (93.1) 14 (87.5) 0.44
 Severity indicators
  APACHE II 22.1 ± 9.4 20.8 ± 8.6 30.1 ± 10.3 < 0.001
  Shock 69 (56.0) 54 (53.5) 15 (93.8) 0.002
  Altered mentation 22 (18.8) 16 (15.8) 6 (37.5) 0.039
 Ventilatory support
  -Invasive 108 (92.3) 92 (91.1) 16 (100.0) 0.46
  -Non-invasive 3 (2.6) 3 (3.0) 0 (0)  
  -Supplemental oxygen 6 (5.1) 6 (5.9) 0 (0)  
  1. Data are presented as number (%), mean ± standard deviation. APACHE = Acute Physiology and Chronic Health Evaluation. a Data was missing for 4 patients. bData was missing for 1 patient