Characteristics | Control casesa (n = 23) | OXA-72 cases (n = 45) | OR(CI 95%) | P value | OXA-23 cases (n = 33) | OR(CI 95%) | P value |
---|---|---|---|---|---|---|---|
Age, median(range) | 76(2,96) | 78(28,94) | 1.02(1.00,1.05) | 0.081 | 78(21,90) | 1.00(0.99,1.03) | 0.460 |
Male gender, n(%) | 22(75.9) | 27(60.0) | 0.32(0.09,1.08) | 0.067 | 23(69.7) | 0.48(0.13,1.79) | 0.484 |
ICU stay, n (%) | 1(4.3) | 27(60.0) | 33.00(4.08,267.04) | 0.001 | 22(66.7) | 44.00(5.23,370.52) | < 0.001 |
Length of stay in the ICU (days), median(range) | 0(0,2) | 5(0,100) | 2.29(1.20,4.37) | 0.012 | 3(0,100) | 2.29(1.03,5.08) | 0.042 |
Predisposing factors | |||||||
 Urinary catheter | 9(39.1) | 27(60.0) | 2.33(0.84,6.52) | 0.106 | 23(69.7) | 3.58(1.17,10.96) | 0.026 |
 Mechanical ventilation | 2(8.7) | 18(40.0) | 7.00(1.46,33.59) | 0.015 | 14(42.4) | 7.74(1.55,38.56) | 0.013 |
 Central venous catheter | 5(21.7) | 14(31.1) | 1.63(0.50,5.26) | 0.417 | 17(51.5) | 3.83(1.15,12.74) | 0.029 |
 Tracheostomy | 1(4.3) | 10(22.2) | 6.29(0.75,52.56) | 0.090 | 11(33.3) | 11.00(1.31,92.63) | 0.027 |
 Transfusion | 1(4.3) | 5(11.1) | 2.75(0.30,25.05) | 0.369 | 7(21.2) | 5.92(0.68,51.92) | 0.108 |
 Nasogastric intubation | 4(17.4) | 28(62.2) | 7.82(2.27,26.91) | 0.001 | 19(57.6) | 6.45(1.79,23.19) | 0.004 |
 Cephalosporin | 12(52.2) | 15(33.3) | 0.46(0.16,1.27) | 0.136 | 12(36.4) | 0.53(0.17,1.55) | 0.242 |
 β-lactam/β-lactamase inhibitor combinations | 12(52.2) | 24(53.3) | 2.61(0.90,7.57) | 0.077 | 12(36.4) | 1.31(0.42,4.07) | 0.645 |
 Quinolone | 3(13.0) | 19(42.2) | 4.87(1.26,18.79) | 0.022 | 10(30.3) | 2.90(0.70,12.02) | 0.143 |
 Carbapenem | 4(17.4) | 21(46.7) | 4.16(1.22,14.18) | 0.023 | 20(60.6) | 7.31(2.02,26.40) | 0.002 |