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Table 1 Clinical characteristics of 111 patients identified as BALF CMV positive or negative, Soochow, 2014–2017

From: Associations between patient clinical characteristics and the presence of cytomegalovirus DNA in the bronchoalveolar lavage fluid of children with recurrent wheezing

Variable

BALF CMV positive (n = 57)

BALF CMV negative (n = 54)

P-value

Age, median (IQR), months

11.0 (6.0–21.5)

14.5 (9.7–23.0)

0.133

Male, n (%)

42 (73.7)

43 (79.6)

0.460

Breastfeeding, n (%)

35 (61.4)

30 (55.6)

0.532

≥ 2 children in household, n (%)

34 (59.6)

37 (68.5)

0.331

Length of hospitalization, median (IQR), days

11.0 (9.0–13.2)

11.0 (8.0–13.0)

0.001

Peripheral blood eosinophils, median (IQR), %

0.7 (0.3–1.3)

0.9 (0.2–2.3)

0.385

IgE, median (IQR), IU/mL

77.1 (11.1–132.2)

46.4 (9.2–160.6)

0.833

Subpopulation of lymphocytes, median (IQR), %

 CD19+CD23+

13.6 (10.5–19.4)

13.3 (9.9–18.1)

0.383

 CD3+

61.3 (52.4–70.9)

65.1 (52.6–70.3)

0.626

 CD3+ CD4+

35.0 (26.9–39.7)

35.3 (31.4–45.1)

0.063

 CD3+CD8+

24.3 (17.6–28.6)

18.5 (15.6–26.2)

0.023

 CD3CD16+CD56+

9.6 (6.3–13.1)

8.9 (5.4–11.7)

0.647

 CD3CD19+

24.6 (18.2–31.1)

21.9 (17.6–30.6)

0.482

Humoral immunity, median (IQR), g/L

 Total IgA

0.43 (0.16–0.66)

0.32 (0.16–0.59)

0.273

 Total IgM

0.89 (0.68–1.46)

0.9 (0.63–1.36)

0.700

 Total IgG

6.09 (4.91–7.93)

5.73 (4.25–7.92)

0.254

Cytology of BALF, median (IQR), %

 Macrophages

50.0 (13.5–87.0)

54.0 (24.5–82.5)

0.554

 Neutrophils

38.0 (10.0–77.5)

36.5 (12.0–62.0)

0.437

 Lymphocytes

4.0 (2.0–9.5)

5.0 (2.0–6.7)

0.954

 Eosinophils

0.0 (0.0–2.0)

0.5 (0.0–6.0)

0.027

  1. BALF bronchoalveolar lavage fluid, CMV cytomegalovirus