Distribution of serotypes and patterns of antimicrobial resistance among commensal Streptococcus pneumoniae in nine European countries

Table 7 Effect of pneumococcal vaccination and vaccination variables (dose, conduction of catch up campaign, year of implementation, vaccine type and extent of vaccination program), on carriage of antimicrobial resistant pneumococcus (resistant to at least one antibiotic) in the participating individuals

Models	Reference variable	Comparative variables	OR*	p value**
Basic model:
Model 1: vaccination	Vaccinated	Not vaccinated	0.60 (0.37–0.96)	0.03**
Model 1: vaccination	Vaccinated	Unknown vaccination status	0.63 (0.33–1.18)	0.15
Models after addition vaccination program characteristics separately:
Model 2: vaccine dose	2 + 1^b	3+1^a	0.91 (0.35–2.32)	0.84
Model 3: catch up campaign conduction	Catch up campaign conducted ^c	No catch up campaign conducted ^d	1.57 (0.65–3.79)	0.32
Model 4: period since vaccine implementation	implemented for one year	implemented for more than one year	1.10 (0.90–1.34)	0.34
Model 5: vaccine type	PCV 10	PCV 7	1.23 (0.39–3.87)	0.72
Model 5: vaccine type	PCV 10	PCV 13	0.87 (0.27–2.72)	0.81
Model 6: extent of vaccination program	risk based and universal ^e	Universal ^f	0.69 (0.17–2.81)	0.61
Model 6: extent of vaccination program	risk based and universal ^e	Risk based ^g	1.07 (0.24–4.69)	0.92

*p < 0.05 is significant
^a) Austria, Hungary, Netherlands, Spain, ^b) Belgium, France, Hungary, Sweden, UK, ^c) Belgium, FR, Hungary, UK, ^d) Austria, Hungary, Netherlands, Spain, Sweden, ^e) France, ^f) Austria, Belgium, Hungary, Netherlands, Sweden, UK, ^g) Hungary, Spain

ISSN: 1471-2334