Hospitalization rates and outcome of invasive bacterial vaccine-preventable diseases in Tuscany: a historical cohort study of the 2000–2016 period

Table 7 Findings of multivariable logistic regression models

Type of IBD	Variable	OR (95% CI)	p-value
IMD (N = 330; p < 0.05; R² = 0.07)	Age group
	<5 years	0.76 (0.25; 2.30)	0.624
	5–17 years	0.79 (0.24; 2.61)	0.696
	18–64 years	1.00
	≥65 years	3.13 (1.14; 8.60)	0.027
	Gender
	male	0.70 (0.30; 1.62)	0.410
	female	1.00
	Charlson Index
	no comorbidities	1.00
	comorbidities	1.58 (0.56; 4.42)	0.385
IPD (N = 1125; p < 0.001; R² = 0.04)	Age group
	<18 years	1.00
	≥18 years	17.43 (2.40; 126.35)	0.005
	Gender
	male	0.81 (0.58; 1.13)	0.217
	female	1.00
	Nationality
	Italian	3.38 (0.80; 14.20)	0.097
	non-Italian	1.00
	Charlson Index
	no comorbidities	1.00
	comorbidities	1.45 (1.03; 2.04)	0.031
Invasive H. influenzae diseases (N = 125; p < 0.001; R² = 0.16)	Age group
	<65 years	1.00
	≥65 years	17.94 (2.16; 148.71)	0.007
	Charlson Index
	no comorbidities	1.00
	comorbidities	0.87 (0.26; 2.92)	0.821

IBD invasive bacterial disease, OR odds ratio, CI confidence interval, IMD invasive meningococcal diseases, IPD invasive pneumococcal diseases

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