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Table 4 Phenotype-genotype association of infections on day 3

From: A barcode of multilocus nuclear DNA identifies genetic relatedness in pre- and post-Artemether/Lumefantrine treated Plasmodium falciparum in Nigeria

 

Genotype n (%)

mdr1–86

mdr1–184

crt-76

K13–580

Phenotype

N

Y

N/Y

Y

F

Y/F

K

T

K/T

C

Y

C/Y

Individuals with parasites on day 3 = 12

0 (0%)

10 (83.3%)

2 (16.7%)

2 (14.3%)

8 (66.6%)

2 (16.7%)

2 (16.7%)

8(66.6%)

2 (16.7%)

12 (100%)

0 (0%)

0 (0%)

Individuals with full clearance of parasites on day 3 = 53

5 (9.43%)

46 (86.8%)

2 (3.8%)

11 (20.8%)

29 (54.7%)

13 (24.5%)

10 (18.9

40 (75.5%)

3 (5.7%)

53 (100%)

0 (0%)

0 (0%)

  1. N86 = mdr1–86 wildtype allele; 86Y = mdr1–86 mutant allele; Y184 = mdr1–184 wildtype allele; 184F = mdr1–184 mutant allele; K76 = crt-76 wildtype allele; 76 T = crt-76 mutant allele; C580 = K13 wildtype allele; 580Y = K13 mutant allele